Results 41 to 50 of about 3,166,315 (255)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Comparison of TyG indices and atherogenic index of plasma with hypertension in the PERSIAN Guilan cohort

Scientific Reports
Hypertension (HTN) is a major global contributor to cardiovascular morbidity and mortality. Insulin resistance is a key mechanistic factor in HTN development, yet its direct measurement is impractical in large population studies.
Ehsan Amini-Salehi, Farahnaz Joukar, Negin Letafatkar, Soheil Hassanipour, Saman Maroufizadeh, Mehrnaz Asgharnezhad, Fariborz Mansour-Ghanaei   +6 more
doaj   +1 more source

The effectiveness of walking exercise on the bowel preparation before colonoscopy: a single blind randomized clinical trial study

BMC Gastroenterology, 2023
Background and Aim Bowel preparation is a crucial factor affecting the diagnostic accuracy of colonoscopy, and few randomized control trials evaluated enhancement in bowel preparation.
Gholamreza Rezamand, Farahnaz Joukar, Ehsan Amini-Salehi, Hamed Delam, Reza Zare, Alireza Samadi, Sara Mavadati, Soheil Hassanipour, Fariborz Mansour-Ghanaei   +8 more
doaj   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Medicinal Plants for Gastrointestinal Diseases

, 2022
Gastrointestinal (GI) diseases are those that affect the digestive tract. This may include sections from the esophagus to the rectum and the liver, gallbladder, and pancreas digestive organs. Gastrointestinal diseases may be acute, chronic, or recurrent.
Duong Thi Hai Linh, Ngo Thi Hue, Linh D.T.H., Bui Thanh Tung, Nhung N.T., Tung B.T., Hue N.T., Nguyen Thi Nhung   +7 more
core   +1 more source

Multi-strain synbiotic and lifestyle modifications on patients with metabolic dysfunction-associated steatotic liver disease (MASLD): a randomized double-blinded placebo-controlled trial

European Journal of Medical Research
Background MASLD is the most common chronic liver disease and the leading cause of liver-related morbidity and mortality globally. While probiotic supplementations show promise as adjunctive therapy, existing trials are limited by the quality of evidence,
Masoud Faghieh Dinavari, Samaneh Abbasian, Amirreza Jabbaripour Sarmadian, Tahereh Vaezi, Tayyebeh Vaezi, Zeinab Nikniaz, Ali Riazi   +6 more
doaj   +1 more source

Efficacy of Sovodak in the Management of Patients Co-infected with HIV/HCV [PDF]

Advanced Pharmaceutical Bulletin, 2020
Purpose: Sofosbuvir (SOF) and daclatasvir (DOC) are suggested for the treatment of hepatitis C virus (HCV) in patients with concomitant HCV and human immunodeficiency virus (HIV). In 2016, Sovodak tablet a combination of SOF and DOC was introduced.
Mohammad Hossein Somi, Bita Sepehri, Zeinab Nikniaz, Roya Sedghi   +3 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Systematic investigation of gastrointestinal diseases in China (SILC): validation of survey methodology [PDF]

, 2009
Background: Symptom-based surveys suggest that the prevalence of gastrointestinal diseases is lower in China than in Western countries. The aim of this study was to validate a methodology for the epidemiological investigation of gastrointestinal symptoms
Li, Q., Wang, R., Zhao Yanfang, Ping Yin, Zhao, Y., Yan Xiaoyan, Yan, H., Halling Katarina, Fang Jiqian, Duowu Zou, Jia He, Yan, X., Sung Joseph, He Jia, Yan Hong, Zou Duowu, Liu Wenbin, Hao, Y., Liu, W., Joseph Sung, Yuantao Hao, Qiang Li, Katarina Halling, Ma, X., Fang, J., He, J., Xiaoping Kang, Ma Xiuqiang, Wenbin Liu, Halling, K., Yin, P., Xiuqiang Ma, Dent John, Yanfang Zhao, Kang, X., Johansson, S., Li Qiang, Wang Rui, Hao Yuantao, Johansson Saga, Hong Yan, Yin Ping, Saga Johansson, Dent, J., Xiaoyan Yan, Rui Wang, Jiqian Fang, John Dent, Sung, J., Kang Xiaoping, Zou, D.   +50 more
core   +2 more sources

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida, Kengo Asahina, Keiichi Osano, Natsumi Saegusa, Kohei Yamamura, Kie Ohkoshi, Miho Shikata, Toshihisa Ishii, Makiko Konishi, Kazuya Takahashi, Kohei Uchimura, Ayumu Nakashima   +11 more
wiley   +1 more source