Results 51 to 60 of about 10,687,454 (378)

Role of the Gut-Brain Axis in the Shared Genetic Etiology Between Gastrointestinal Tract Diseases and Psychiatric Disorders

JAMA psychiatry, 2023
Key Points Question To what extent are shared genetic determinants in the comorbidities and associations between gastrointestinal tract diseases and psychiatry disorders involved in the gut-brain axis? Findings In this genome-wide pleiotropic association
Weiming Gong, Ping Guo, Yuanming Li, Lu Liu, Ran Yan, Shu Liu, Shukang Wang, F. Xue, Xiang Zhou, Zhongshang Yuan   +9 more
semanticscholar   +1 more source

Goblet cells: guardians of gut immunity and their role in gastrointestinal diseases

eGastroenterology
Goblet cells (GCs) are specialised guardians lining the intestine. They play a critical role in gut defence and immune regulation. GCs continuously secrete mucus creating a physical barrier to protect from pathogens while harbouring symbiotic gut ...
F. R. Tonetti, Á. Eguileor, C. Llorente
semanticscholar   +1 more source

Phage Therapy in Gastrointestinal Diseases

Microorganisms, 2020
Gastrointestinal tract microbiota plays a key role in the regulation of the pathogenesis of several gastrointestinal diseases. In particular, the viral fraction, composed essentially of bacteriophages, influences homeostasis by exerting a selective ...
B. Gutiérrez, P. Domingo-Calap
semanticscholar   +1 more source

The oral microbiome and oral and upper gastrointestinal diseases

Journal of Oral Microbiology
Background Microbiomes are essential components of the human body, and their populations are substantial. Under normal circumstances, microbiomes coexist harmoniously with the human body, but disturbances in this equilibrium can lead to various diseases.
Sifan Liu, Shidong Wang, Nan Zhang, Peng Li   +3 more
semanticscholar   +1 more source

Time trend occurrence of duodenal intraepithelial lymphocytosis and celiac disease in an open access endoscopic population [PDF]

, 2017
Background: Duodenal intraepithelial lymphocytosis (DIL) is a histological finding characterized by the increase of intraepithelial CD3T-lymphocytes over the normal value without villous atrophy, mostly associated to coeliac disease (CD), Helicobacter ...
Annibale, B., Corleto, Vd, Di Giulio, E, Galli, G, Lahner, E, Pilozzi, E, Purchiaroni, F, Sacchi, Mc   +7 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Seroprevalence of CMV infection in patients with active ulcerative colitis and underlying factors of pathogenicity

BMC Infectious Diseases
Background Cytomegalovirus (CMV) infection has garnered increasing attention in the context of active ulcerative colitis (UC), a chronic IBD, characterized by periods of remission and relapse.
Farahnaz Joukar, Mohammad Almasi, Narges Eslami, Niloofar Faraji, Kurosh Askari, Ghazale Ghorbani, Navid Yusefi, Fariborz Mansour-Ghanaei   +7 more
doaj   +1 more source

A Fibreoptic Endoscopic Study of Upper Gastrointestinal Bleeding at Bugando Medical Centre in Northwestern Tanzania: a Retrospective Review of 240 Cases. [PDF]

, 2012
Upper gastrointestinal (GI) bleeding is recognized as a common and potentially life-threatening abdominal emergency that needs a prompt assessment and aggressive emergency treatment.
A Elghuel, A Timraz, AB Olokoba, AG Kankaria, Anthony Liwa, C Meaden, C Zaltman, D Pateron, DA Peura, DE Elliott, DJ Cook, DJ Exon, Eliasa Mkongo, EM Vreeburg, FK Chan, G Theocharis, GS Kibiki, HC Wolfsen, HM Salih, Hyasinta Jaka, J Chasawat, J Villanueva Palacios, JA Forrest, K Aoki, K Kivkin, K Palmer, M Suba, M Urassa, Mabula D Mchembe, Mariam Mirambo, ME Van Leerdam, Mheta Koy, MJ Kaviani, MN Lakhwani, N Sarin, NK Arora, P Vlavianos, Phillipo L Chalya, Rodrick Kabangila, S Mustapha, SA Hearnshaw, T Alempijevic, TA Rockall, TA Rockall, V Balderas, Wolfgang Scheppach   +45 more
core   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

A Patient Flow Analysis: Identification of Process Inefficiencies and Workflow Metrics at an Ambulatory Endoscopy Unit

Canadian Journal of Gastroenterology and Hepatology, 2016
Background. The increasing demand for endoscopic procedures coincides with the paradigm shift in health care delivery that emphasizes efficient use of existing resources.
Rowena Almeida, William G. Paterson, Nancy Craig, Lawrence Hookey   +3 more
doaj   +1 more source