Results 61 to 70 of about 381,169 (287)

Recent advances in vasoactive intestinal peptide physiology and pathophysiology: focus on the gastrointestinal system. [PDF]

, 2019
Vasoactive intestinal peptide (VIP), a gut peptide hormone originally reported as a vasodilator in 1970, has multiple physiological and pathological effects on development, growth, and the control of neuronal, epithelial, and endocrine cell functions ...
Akiba, Yasutada, Iwasaki, Mari, Kaunitz, Jonathan D   +2 more
core  

The association between waist-to-hip ratio (WHR) with diabetes in the PERSIAN Guilan cohort study population

BMC Endocrine Disorders
Background Waist circumference (WC), or waist-to-hip ratio (WHR), potentially offers a more accurate reflection of intra-abdominal fat accumulation and could serve as a superior predictor of type 2 diabetes mellitus (T2DM) risk compared to BMI.
Masoome Aghaei, Farahnaz Joukar, Soheil Hasanipour, Zahra Abbasi Ranjbar, Mohammadreza Naghipour, Fariborz Mansour-Ghanaei   +5 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Identification of medicinal plants of Urmia for treatment of gastrointestinal disorders [PDF]

, 2014
The gastrointestinal tract is one of the most important organs of the human body and is vulnerable to different diseases. Available drugs often have low efficacy or are associated with many adverse effects.
Bahmani, Mahmoud., Rafieian-Kopaei, Mahmoud., Zargaran, Arman.   +2 more
core   +2 more sources

Examining the factor structure of the Pittsburgh Sleep Quality Index and its determinants among GI cancer patients

BMC Cancer
Background Poor sleep quality is one of the prevalent manifestations experienced by cancer patients. There is a lack of research focusing specifically on sleep quality and affecting factors in Gastrointestinal (GI) cancer patients.
Masoudreza Sohrabi, Ali Gholami, Parvin Hassanzadeh, Sara Hatami, Hosein Ajdarkosh, Farhad Zamani, Azam Doustmohammadian   +6 more
doaj   +1 more source

Opportunity Costs of Gastrointestinal Endoscopic Training in Canada

Canadian Journal of Gastroenterology, 2010
BACKGROUND: No data exist to define the opportunity costs related to instruction in endoscopic procedures in Royal College of Physicians and Surgeons of Canada-accredited teaching centres. Academic and institutional administrators expect staff to achieve
WT Depew, LC Hookey, SJ Vanner, JA Louw, CE Lowe, MJ Ropeleski, MJ Beyak, A Lazarescu, WG Paterson   +8 more
doaj   +1 more source

Gastrointestinal Diseases of the Ferret

Veterinary Clinics of North America: Exotic Animal Practice, 2005
Gastrointestinal (GI) disease is common in pet ferrets. According to Delaney, unique ferret anatomy and physiology, including rapid GI transit time, and short, simple GI tract predisposes to GI disease [1]. Etiologies include bacteria, including helicobacter infections, virus, parasites, inflammatory conditions, neoplasia, foreign body-related diseases,
openaire   +2 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

EFSUMB Recommendations and Guidelines for Gastrointestinal Ultrasound - Part 1: Examination Techniques and Normal Findings (Long version). [PDF]

, 2016
▼ In October 2014 the European Federation of Societies for Ultrasound in Medicine and Biology formed a Gastrointestinal Ultrasound (GIUS) task force group to promote the use of GIUS in a clinical setting.
Calabrese, E., Dietrich, C. F., Dirks, K., Gilja, O. H., Hausken, T., Higginson, A., Hollerweger, A., Maaser, C., Maconi, G., Nuernberg, D., Nylund, K., Pallotta, Nadia, Ripolles, T., Romanini, L., Saftoiu, A., Serra, C., Sporea, I.   +16 more
core   +3 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source