Results 61 to 70 of about 837,691 (363)

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Peculiarities of the formation of exocrine pancreatic insufficiency in patients with primary osteoarthritis under conditions of comorbidity [PDF]

, 2023
Summary.  The comorbidity of primary OA and diseases of the gastrointestinal tract, which EPI accompanies, is an extremely relevant, complex, and unstudied problem of modern medicine, as it has a number of unsolved problems both in the treatment and
Halabitska, Iryna
core   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Recurrent Gastrointestinal Bleeding in a Man with Osler-Weber-Rendu Syndrome and Intestinal Varices

Canadian Journal of Gastroenterology, 1988
A patient with Osler-Weber-Rendu disease and idiopathic intestinal varices who presented with recurrent gastrointestinal hemorrhage and iron deficiency anemia is reported. The unique coexistence of these two rare disorders is discussed and the literature
Robert N. Clark, William G. Paterson, Laurington R. DaCosta, Ivan T. Beck   +3 more
doaj   +1 more source

Recent advancement in daignosis of gastrointestinal diseases [PDF]

, 2015
Gastrointestinal diseases refer to ulcerative disorders of the upper gastrointestinal tract. Stomach acids and some enzymes can damage the lining of the G.I. tract if natural protective factors are not functioning normally.
Khare, Pragati, Saraswat, Pranit, Tiwari, Ritesh   +2 more
core   +2 more sources

The role of the gastrointestinal tract in the pathogenesis of rheumatic diseases [PDF]

, 2016
Dysregulation of the intestinal epithelial barrier in genetically susceptible individuals may lead to both intestinal and extraintestinal autoimmune disorders.
CICCIA, Francesco, FERRANTE, Angelo, GUGGINO, Giuliana, TRIOLO, Giovanni   +3 more
core   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Gastrointestinal Diseases of the Ferret

Veterinary Clinics of North America: Exotic Animal Practice, 2005
Gastrointestinal (GI) disease is common in pet ferrets. According to Delaney, unique ferret anatomy and physiology, including rapid GI transit time, and short, simple GI tract predisposes to GI disease [1]. Etiologies include bacteria, including helicobacter infections, virus, parasites, inflammatory conditions, neoplasia, foreign body-related diseases,
openaire   +2 more sources

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

Examining the factor structure of the Pittsburgh Sleep Quality Index and its determinants among GI cancer patients

BMC Cancer
Background Poor sleep quality is one of the prevalent manifestations experienced by cancer patients. There is a lack of research focusing specifically on sleep quality and affecting factors in Gastrointestinal (GI) cancer patients.
Masoudreza Sohrabi, Ali Gholami, Parvin Hassanzadeh, Sara Hatami, Hosein Ajdarkosh, Farhad Zamani, Azam Doustmohammadian   +6 more
doaj   +1 more source