Results 111 to 120 of about 149,354 (358)

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

Advanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera, Suneesh Thilak, Asha Patel, Prashant Nasa, Zubair Ahmed, Lorraine Jacques, William J. Scotton, Cyril Chacko, Randeep Mullhi, Ruoling Chen, Vikram Patil, Suresh Renukappa, Tonny Veenith   +12 more
wiley   +1 more source

A Single‐Component Adhesive Sponge Based on Blood‐Triggered and Autopenetrative Adhesion for Robust Vascular Closure

Advanced Science, EarlyView.
This study presents MonoSeal, a single‐component adhesive sponge powered by the novel Autopenetrative Adhesion (APA) mechanism. Unlike traditional adhesives, which require external stimuli, APA enables strong tissue adhesion under dynamic, high‐pressure bleeding conditions. MonoSeal's ability to autonomously seal large‐size arterial defects underscores
Rong Wang, Weishi Zheng, Yuxuan Huang, Rui Zhang, Yi Zhang, Jingying Yan, Yuqing Gu, Jingyun Xi, Tun Yuan, Hua Su, Xianzhu Zhang, Xiaozhao Wang, Shaohui Xiong, Zhenfeng Cheng, Hongwei Ouyang, Yi Hong   +15 more
wiley   +1 more source

MALLORY-WEISS SYNDROME: REVIEW OF A THIRTEEN-YEAR PERIOD

Zdravniški Vestnik, 2008
BACKGROUND Acute upper gastrointestinal hemorrhage is a frequent problem of emergency medicine.Mallory-Weiss syndrome, a laceration at the esophagogastric junction, is an uncommonsource of acute upper gastrointestinal hemorrhage. The purpose of the study
Pavel Skok, Dejan Kupnik, Grujica Vujnović   +2 more
doaj  

Endoscopic closure devices: A review of technique and application for hemostasis

International Journal of Gastrointestinal Intervention, 2019
Acute gastrointestinal bleeding is a common, yet challenging, and potentially problematic medical emergency for clinicians to manage. Given its significantly high health care associated costs and increased morbidity and mortality rate, new endoscopic ...
Jennifer Wellington, Andrew Canakis, Raymond Kim   +2 more
doaj   +1 more source

Use of Plasmapheresis and Immunosuppressants to Treat Diffuse Alveolar Hemorrhage in a Patient with Granulomatosis with Polyangiitis. [PDF]

, 2019
Granulomatosis with polyangiitis (GPA) is a systemic granulomatous inflammatory disease characterized by small-to-medium vessel vasculitis due to Central Anti-Neutrophil Cytoplasmic Antibody (C-ANCA).
Sattar, Yasar, Susheela, Ammu Thampi, Ullah, Waqas, Usman, Norina, Zafrullah, Fnu   +4 more
core   +1 more source

Photobiomodulation Strengthens Muscles via Its Dual Functions in Gut Microbiota

Advanced Science, EarlyView.
Non‐invasive photobiomodulation therapy (PBMT) enhances muscle endurance by rewiring the gut‐muscle axis. PBMT preserves gut epithelial integrity and enriches beneficial anaerobes, driving metabolites such as butyrate, spermidine, and L‐carnitine that supercharge mitochondrial energy in skeletal muscles.
Prabhat Upadhyay, Asmita Banstola, Brijesh Bhayana, Mei X. Wu   +3 more
wiley   +1 more source

Scintigraphic Detection of Active Bleeding into the Intra-Abdominal Hematoma

Siriraj Medical Journal, 2008
Although Tc-99m labeled red blood cells (Tc-99m RBC) imaging has been well established for localization of acute gastrointestinal bleeding, the use for detection of bleeding sites outside the gastrointestinal tract has not been widely used.
Pawana Pusuwan, Suraphong Lueangwuttiwong   +1 more
doaj  

The association between hemoglobin concentration and neurologic outcome after cardiac arrest. [PDF]

, 2016
PURPOSE: The purpose of the study is to determine the association between hemoglobin concentration (Hgb) and neurologic outcome in postarrest patients. METHODS: We conducted a retrospective cohort study using the Penn Alliance for Therapeutic Hypothermia
Dodampahala, Kalani, Gaieski, David F., Goyal, Munish, Grossestreuer, Anne V., Johnson, Nicholas J., Perman, Sarah M., Rosselot, Babette   +6 more
core   +1 more source

An Inflammation‐Targeting Engineered Probiotic Escherichia coli Nissle 1917 with High Anti‐TNF‐α Nanobody Secretion Efficacy Alleviates Ulcerative Colitis

Advanced Science, EarlyView.
Ulcerative colitis therapy requires precise drug targeting. This study engineers a probiotic E. coli Nissle 1917 to surface‐display ANXA5, enabling specific binding to phosphatidylserine (PS) exposed on inflamed colonic epithelium for enhanced targeting and colonization.
Siqi Hua, Kaiqiang Li, Pengyou Shang, Lina Liu, Jiayu Pan, Bo Zhu, Zichun Hua   +6 more
wiley   +1 more source

A Pill That Prints‐An Ingestible Bioprinter for Non‐Invasive Structured Bioink Deposition

Advanced Science, EarlyView.
A first‐of‐a‐kind swallowable bioprinter performs in‐situ bioink deposition and patterning directly over disease sites without tethers, electronics, or invasive surgery. Combining magnetic guidance with near‐infrared triggering enables functionality within a small footprint.
Sanjay Manoharan, Vivek Subramanian
wiley   +1 more source