Results 111 to 120 of about 96,065 (282)

The High‐Altitude Adaptation Characteristics of Microbiota‐Host Cross‐Talk in Yak Gastrointestinal Track

Advanced Science, EarlyView.
In this study, a single‐cell atlas of 117,019 yak gastrointestinal cells across 54 subtypes identified HNF4A and SREBF2 as key transcription factors targeting MYO6 gene. Cross‐species and multi‐omics analyses reveals epithelial cells as key regulators that, through interactions with microbes, particularly Bacillus, facilitate flexible energy supply and
Chun Huang, Minghao Zhang, Qingbo Zheng, Qinran Yu, Guowu Yang, Wenwen Ren, Xiaoming Ma, Yongfu La, Pengjia Bao, Min Chu, Xian Guo, Chunnian Liang, Ping Yan   +12 more
wiley   +1 more source

Lactobacillus Salivarius‐Derived Indole‐3‐Acetic Acid Promotes AHR‐PARP1 Axis‐Mediated DNA Repair to Mitigate Intestinal Aging

Advanced Science, EarlyView.
Indole‐3‐acetic acid (IAA) acting as one of the aryl hydrocarbon receptor (AHR) endogenous ligands is identified to be derived from Lactobacillus salivarius via its catalytic enzyme (ALDH) rather than host cells. Lactobacillus salivarius and IAA supplementation effectively mitigate intestinal aging by facilitating AHR‐poly (ADP‐ribose) polymerase 1 ...
Zheng Cao, Cui Zhang, Hehua Lei, Weichuan Lin, Wenkai Yu, Xin Gao, Yanmeng He, Xinzhi Li, Qingwei Xiang, Zhiwen Zhang, Weifei Luo, Andrew D. Patterson, Limin Zhang, Gang Chen   +13 more
wiley   +1 more source

A pathophysiologic framework for the overlap of disorders of gut-brain interaction and the role of the gut microbiome

Gut Microbes
The International Rome Committee defines Disorders of Gut-Brain Interactions (DGBI) based upon distinct combinations of chronic and/or recurrent unexplained gastrointestinal symptoms. Yet patients often experience overlapping DGBI.
Ayesha Shah, Yeong Yeh Lee, Hidekazu Suzuki, Joash Tan-Loh, Kewin Tien Ho Siah, Kok-Ann Gwee, Thomas Fairlie, Nicholas J. Talley, Uday C Ghoshal, Yen-Po Wang, Yong Sung Kim, Gerald Holtmann   +11 more
doaj   +1 more source

SIV Infection-Mediated Changes in Gastrointestinal Bacterial Microbiome and Virome Are Associated with Immunodeficiency and Prevented by Vaccination [PDF]

, 2016
Scott A. Handley, Chandni Desai, Guoyan Zhao, Lindsay Droit, Cynthia L. Monaco, Andrew Schroeder, Joseph P. Nkolola, Megan E. Norman, Andrew D. Miller, David Wang, Dan H. Barouch, Herbert W. Virgin   +11 more
openalex   +1 more source

The Gut Microbiome in Enteric Viral Infections: Underlying Mechanisms and Therapeutic Approaches

Microorganisms
Despite growing recognition of the role of the gut microbiome in host health and in modulating pathogen activity, the dynamic and reciprocal relationship between enteric viruses and the gut microbial ecosystem remains insufficiently defined and requires ...
Alejandro Borrego-Ruiz, Juan J. Borrego
doaj   +1 more source

Gut microbiome diversity in acute infective and chronic inflammatory gastrointestinal diseases in North India [PDF]

, 2016
Saurabh Kedia, Ritika Rampal, Jaishree Paul, Vineet Ahuja   +3 more
openalex   +1 more source

Comparison of Pre‐ and Postoperative Gut Microbiota Diversity in Patients With Rectal Cancer Undergoing Stoma Creation and Closure

Annals of Gastroenterological Surgery, EarlyView.
We investigated the impact of temporary stoma creation and closure on gut microbiota diversity in rectal cancer patients. 16S rRNA sequencing revealed that microbial diversity significantly decreased postoperatively in the stoma group but remained stable in non‐stoma patients.
Yusuke Suzuki, Wataru Osumi, Kohei Taniguchi, Nahoko Kato‐Kogoe, Shoichi Sakaguchi, Shota Nakamura, Yoshiro Imai, Takashi Nakano, Takaaki Ueno, Sang‐Woong Lee   +9 more
wiley   +1 more source

Gastrointestinal microbiome and cholelithiasis: Prospect in the nervous system. [PDF]

World J Gastroenterol, 2023
Mancha Chahuara M, Lopez Tufino LDM, Mugruza-Vassallo CA.   +2 more
europepmc   +1 more source

Gut microbiota therapy in gastrointestinal diseases

Frontiers in Cell and Developmental Biology
The human gut microbiota, consisting of trillions of microorganisms, plays a crucial role in gastrointestinal (GI) health and disease. Dysbiosis, an imbalance in microbial composition, has been linked to a range of GI disorders, including inflammatory ...
Hanif Ullah, Safia Arbab, Chengting Chang, Saira Bibi, Nehaz Muhammad, Sajid Ur Rehman, Suleman, Suleman, Irfan Ullah, Inam Ul Hassan, Yali Tian, Ka Li   +11 more
doaj   +1 more source

Multiple Sampling Capsule Robot for Studying Gut Microbiome

Advanced Intelligent Systems, EarlyView.
A multiple sampling capsule robot (MSCR) is developed for longitudinal gut microbiome analysis. Employing electromagnetic field control, the MSCR can locomote actively, precisely align the selected channel, and collect up to six microbiome samples with minimal cross‐contamination.
Sanghyeon Park, Manh Cuong Hoang, Jayoung Kim, Sukho Park   +3 more
wiley   +1 more source