Results 121 to 130 of about 774,427 (331)

Gut Parabacteroides distasonis‐derived Indole‐3‐Acetic Acid Promotes Phospholipid Remodeling and Enhances Ferroptosis Sensitivity via the AhR‐FASN Axis in Bladder Cancer

Advanced Science, EarlyView.
Indole‐3‐acetic acid (3‐IAA) derived from gut P. distasonis binds to AhR in bladder cancer cells and downregulates FASN transcription, thereby increasing sensitivity to ferroptosis and suppressing the development of bladder tumors. Specifically, 3‐IAA treatment leads to an increase in the proportion of PC/PE‐PUFAs and a decrease in the proportions of ...
Weijia Li, Wentai Shangguan, Wenxue Huang, Jie Zhao, Yuexuan Zhu, Ming Xie, Yao Yu, Qishen Yang, Jun Zheng, Lin Yang, Qi Sun, Leqian Li, Xinhang Shi, Yongyuan Xiao, Hai Huang, Bisheng Cheng, Peng Wu   +16 more
wiley   +1 more source

Alterations to the Gastrointestinal Microbiome Associated with Methamphetamine Use among Young Men who have Sex with Men. [PDF]

, 2019
Methamphetamine (MA) use is a major public health problem in the United States, especially among people living with HIV (PLWH). Many MA-induced neurotoxic effects are mediated by inflammation and gut microbiota may play a role in this process, yet the ...
Aldrovandi, Grace M, Bolan, Robert, Brookmeyer, Ron, Cook, Ryan R, Fulcher, Jennifer A, Gorbach, Pamina M, Javanbakht, Marjan, Lee, David J, Li, Fan, Shoptaw, Steve, Tobin, Nicole H, Woodward, Cora   +11 more
core  

Factors Associated with the Diversification of the Gut Microbial Communities within Chimpanzees from Gombe National Park. [PDF]

, 2012
The gastrointestinal tract harbors large and diverse populations of bacteria that vary among individuals and within individuals over time. Numerous internal and external factors can influence the contents of these microbial communities, including diet ...
A. E. Pusey, Arumugam, B. H. Hahn, Caporaso, Caporaso, Constable, Degnan, E. E. Wroblewski, E. V. Lonsdorf, H. Ochman, J. Goodall, Keele, Ley, M. L. Wilson, Mackie, Mariat, McKenna, Ochman, P. H. Degnan, Palmer, R. S. Rudicell, Savage, Turnbaugh, Turnbaugh, Wroblewski, Yildirim, Zoetendal   +26 more
core   +1 more source

Probiotic‐Enhanced Porous Bio‐Hybrids with Inflammatory Targeting, ROS Scavenging, and Long‐Term Drug Release for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
Probiotic‐enhanced porous bio‐hybrids (E‐xPAM@ASA), developed by coupling the drug‐loaded hairy microporous nanospheres xPAM@ASA with probiotic EcN, integrate inflammatory‐targeting, ROS scavenging, and long‐term release of 5‐ASA to improve inflammation and regulate microbiota structure in the DSS‐induced colitis model, providing an advanced strategy ...
Luna Quan, Yang Ouyang, Weiwen Liang, Zixin Chen, Dongtian Miao, Bingna Zheng, Dingcai Wu, Rongkang Huang   +7 more
wiley   +1 more source

Multiple Sampling Capsule Robot for Studying Gut Microbiome

Advanced Intelligent Systems, EarlyView.
A multiple sampling capsule robot (MSCR) is developed for longitudinal gut microbiome analysis. Employing electromagnetic field control, the MSCR can locomote actively, precisely align the selected channel, and collect up to six microbiome samples with minimal cross‐contamination.
Sanghyeon Park, Manh Cuong Hoang, Jayoung Kim, Sukho Park   +3 more
wiley   +1 more source

Impact of microbiome-based interventions on gastrointestinal pathogen colonization in the intensive care unit

Therapeutic Advances in Gastroenterology, 2020
In the intensive care unit (ICU), colonization of the gastrointestinal tract by potentially pathogenic bacteria is common and often precedes clinical infection.
Alexa Choy, Daniel E. Freedberg
doaj   +1 more source

Relating the metatranscriptome and metagenome of the human gut [PDF]

, 2014
Although the composition of the human microbiome is now wellstudied, the microbiota’s \u3e8 million genes and their regulation remain largely uncharacterized.
Boylan, Matthew R., Chan, Andrew T., Ciulla, Dawn, Earl, Ashlee M., Franzosa, Eric A., Garrett, Wendy S., Gevers, Dirk, Giannoukos, Georgia, Huttenhower, Curtis, Izard, Jacques, Morgan, Xochitl C., Reyes, Joshua, Segata, Nicola, Waldron, Levi   +13 more
core   +2 more sources

The Equine Gastrointestinal Microbiome: Impacts of Age and Obesity

Frontiers in Microbiology, 2018
Gastrointestinal microbial communities are increasingly being implicated in host susceptibilities to nutritional/metabolic diseases; such conditions are more prevalent in obese and/or older horses.
P. Morrison, C. J. Newbold, E. Jones, H. Worgan, D. Grove-White, A. Dugdale, C. Barfoot, P. Harris, C. Argo   +8 more
semanticscholar   +1 more source

Mycosis Fungoides, Sézary Syndrome, and Cutaneous B‐Cell Lymphomas: 2025 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Disease Overview Primary cutaneous lymphomas are a rare and heterogeneous group of extranodal lymphomas that require the integration of clinical and histopathologic data for classification and treatment. Diagnosis Diagnosis and disease classification is based on histopathologic review and immunohistochemical staining of an appropriate skin ...
Alexandra C. Hristov, Trilokraj Tejasvi, Ryan A. Wilcox   +2 more
wiley   +1 more source

Association of Chorioamnionitis with Aberrant Neonatal Gut Colonization and Adverse Clinical Outcomes. [PDF]

, 2016
ObjectiveChorioamnionitis (inflammation of the placenta and fetal membranes) and abnormal gastrointestinal colonization have been associated with an increased risk of sepsis and death in preterm infants, but whether chorioamnionitis causes abnormal ...
Ambalavanan, Namasivayam, Kallapur, Suhas G, Morrow, Ardythe L, Puri, Kriti, Schibler, Kurt R, Taft, Diana H   +5 more
core   +1 more source