Results 151 to 160 of about 155,584 (325)

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

Clinical Pharmacology &Therapeutics, EarlyView.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Gastrointestinal Diseases and Gut Microbiome Therapy

Xiehe Yixue Zazhi, 2022
Gut microbiome regulates host metabolism and immunity via their metabolites, secretions, and cellular components, and protects the host from pathogen invasion. Low diversity and dysfunction of the gut microbiome caused by environmental changes, unhealthy dietary habits and lifestyles, and antibiotics abuse are closely related to disease pathogenesis ...
HUANG Ziyu, ZUO Tao, LAN Ping
openaire   +1 more source

The oral microbiome and oral and upper gastrointestinal diseases

Journal of Oral Microbiology
Background Microbiomes are essential components of the human body, and their populations are substantial. Under normal circumstances, microbiomes coexist harmoniously with the human body, but disturbances in this equilibrium can lead to various diseases.
Sifan Liu, Shidong Wang, Nan Zhang, Peng Li   +3 more
doaj   +1 more source

The Influence of Omega‐3 Fatty Acids and Probiotics on Hippocampal Inflammation and Glial Cells in a Chronic Anorexia Nervosa Rat Model

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe eating disorder associated with brain volume reduction, glial cell loss, microbiome alterations, and dysregulated pro‐inflammatory mechanisms. However, the underlying cellular mechanisms remain inadequately elucidated, and interventions addressing these alterations are lacking.
A. C. Thelen, N. Andreani, N. M. Korten, M. Neumann, V. Verspohl, M. van Egmond, L. Kneisel, C. Voelz, L. Blischke, J. F. Baines, J. Baier, J. Schumacher, F. Kiessling, B. Herpertz‐Dahlmann, C. Beyer, L. Keller, J. Seitz, S. Trinh   +17 more
wiley   +1 more source

Gastrointestinal sodium absorption, microbiome, and hypertension [PDF]

Nature Reviews Cardiology, 2017
Ricardo S, Mishima, Adrian D, Elliott, Prashanthan, Sanders, Dominik, Linz   +3 more
openaire   +2 more sources

The impact of iron supplementation on the preterm neonatal gut microbiome: A pilot study.

PLoS ONE
ObjectiveThe gastrointestinal microbiome in preterm infants exhibits significant influence on optimal outcomes-with dysbiosis shown to substantially increase the risk of the life-threatening necrotizing enterocolitis.
Matthew VanOrmer, Maranda Thompson, Melissa Thoene, Jean-Jack Riethoven, Sathish Kumar Natarajan, Corrine Hanson, Ann Anderson-Berry   +6 more
doaj   +1 more source

Maternal and neonatal microbiome diversity and metabolic pathways are modified by a gastrointestinal nematode in pregnant and lactating mice

, 2020
Manjurul Haque
openalex   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

A pathophysiologic framework for the overlap of disorders of gut-brain interaction and the role of the gut microbiome

Gut Microbes
The International Rome Committee defines Disorders of Gut-Brain Interactions (DGBI) based upon distinct combinations of chronic and/or recurrent unexplained gastrointestinal symptoms. Yet patients often experience overlapping DGBI.
Ayesha Shah, Yeong Yeh Lee, Hidekazu Suzuki, Joash Tan-Loh, Kewin Tien Ho Siah, Kok-Ann Gwee, Thomas Fairlie, Nicholas J. Talley, Uday C Ghoshal, Yen-Po Wang, Yong Sung Kim, Gerald Holtmann   +11 more
doaj   +1 more source