Results 171 to 180 of about 110,779 (256)

Pioneering the canine model in microbiota–gut–brain research for social and affective disorders

open access: yesiMetaOmics, EarlyView.
This commentary highlights the translational potential of canine models in investigating the microbiota–gut–brain (MGB) axis, focusing on their relevance to human social cognition and affective disorders, including major depressive disorder and autism spectrum disorder.
Yun Yu   +8 more
wiley   +1 more source

Fibre supplementation alters the gastrointestinal microbiome, the microbial metabolites and indicators of neurodegeneration in a mouse model of Alzheimer´s disease. [PDF]

open access: yesSci Rep
Böswald LF   +9 more
europepmc   +1 more source

Harnessing microbial metabolism and nutrition to target the gut–mammary axis for better livestock production and health

open access: yesiMetaOmics, EarlyView.
The gut–mammary axis integrates intestinal health with mammary function through neural, endocrine, and immune pathways. Nutritional interventions (probiotics, prebiotics, metabolites) improve gut microecology, generating microbial signals that travel via the axis to the mammary gland. There, they relieve inflammation, enhance milk quality and lactation,
Aolong Zhou   +29 more
wiley   +1 more source

The relationship between the early-life gastrointestinal microbiome and childhood nocturnal cough. [PDF]

open access: yesJ Allergy Clin Immunol
Eapen AA   +10 more
europepmc   +1 more source

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

open access: yesiMetaOmics, EarlyView.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie   +12 more
wiley   +1 more source

The gut microbiome organ

open access: yesiMeta, EarlyView.
The gut microbiome can be conceptualized as a distributed organ‐like functional system with spatially structured organization, broad biochemical capacity, and continuous bidirectional communication with the host. By transforming dietary, host‐derived, and environmental substrates into bioactive metabolites with endocrine‐like, immunomodulatory, and ...
Yang Bi   +22 more
wiley   +1 more source

Gut microbiota‐mediated immune and metabolic dysregulation in coronary artery disease progression and prognosis

open access: yesiMeta, EarlyView.
The gut microbiota has emerged as a metabolically active endocrine‐like organ with a crucial role in coronary artery disease (CAD), yet its contribution to adverse clinical outcomes remains incompletely understood. In this prospective cohort of 319 participants, we integrated metagenomic and metabolomic profiling with longitudinal follow‐up over a ...
Honghong Liu   +10 more
wiley   +1 more source

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