Results 271 to 280 of about 96,065 (282)
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Therapeutic implications of the gastrointestinal microbiome
Current Opinion in Pharmacology, 2018Gut microbiome is an integral part of the metabolic machinery that contributes to normal host function. The advent of next generation sequencing technologies has allowed an in-depth investigation of the microbiome at various body sites including microbes which are challenging to culture. The same technologies have revealed the metabolic capacity of the
Purna C. Kashyap, Eamonn Mm Quigley
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The influence of the gastrointestinal microbiome on infant colic
Expert Review of Gastroenterology & Hepatology, 2020Although infantile colic is relatively frequent, its pathophysiology is not yet understood. The aim of this paper is to provide a better understanding of the link between infantile colic and the gastrointestinal microbiome.The gastro-intestinal microbiome may already start to develop in the womb and grows exponentially immediately after birth.
Ouald Chaib, Abdelhalim +3 more
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Update on the Gastrointestinal Microbiome in Systemic Sclerosis
Current Rheumatology Reports, 2018Accumulating evidence suggests that gut microbiota affect the development and function of the immune system and may play a role in the pathogenesis of autoimmune diseases. The purpose of this review is to summarize recent studies reporting gastrointestinal microbiota aberrations associated with the systemic sclerosis disease state.The studies described
Bellocchi, C., Volkmann, E. R.
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Gut Microbiome and Gastrointestinal Disorders
2021The human gut harbors more than 1014 microorganisms, with bacteria being the main population. Gut microbial composition and diversity participates in vital physiologic and immunologic processes maintaining host homeostasis. The disruption of the healthy microbial structure has been associated with various gastrointestinal disorders including ...
Maria Gazouli +2 more
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Microbiome in Human Gastrointestinal Cancers
2021Human gastrointestinal tract houses several millions of microbes, with which they form complex symbiotic and mutualistic relationships. The resident microbes encode unique genes that are important in several host beneficial processes. As such, alteration of the optimal composition and ecology of human gastrointestinal microbes can be detrimental to the
Olabisi Oluwabukola Coker, Jun Yu
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Nanoparticle effects on gastrointestinal microbiome
Nanomedicine: Nanotechnology, Biology and Medicine, 2016potential as drug and gene delivery vehicles due to the insufficient morphological stability. Therefore, we developed a cerasome with a liposomal bilayer structure and an atomic layer of inorganic polyorganosiloxane networks on its surface by molecularly designed lipidic organoalkoxysilane (Figure 1).
Weiyue Feng +3 more
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Fecal Microbiome Does Not Represent the Microbiome of the Gastrointestinal Tract
SSRN Electronic Journal, 2020Although gut microbiome contributes to the traits and diseases of its host as much as its own genes, current researches based on fecal microbiome have resulted many inconsistent and often contradictory data on how gut microbiome affects its host. In this study using α- and β-diversity analyses on mouse gastrointestinal (GI) contents, we showed that the
Enkhchimeg Lkhagva +5 more
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The gastrointestinal tract microbiome, probiotics, and mood
Inflammopharmacology, 2014Mental health is closely linked to physical health. Depression (e.g., major depression) is highly prevalent worldwide and a major cause of disability. In a subgroup with treatment-resistant depression, standard pharmacotherapy interventions provide small if any incremental improvement in patient outcomes and may also require the application of an ...
Vitetta, Luis +2 more
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The potential for probiotic manipulation of the gastrointestinal microbiome
Current Opinion in Biotechnology, 2012Multiple internal and external sites of the healthy human body are colonized by a diversity of symbiotic microbes. The microbial assemblages found in the intestine represent some of the most dense and diverse of these human-associated ecosystems. Unsurprisingly, the enteric microbiome, that is the totality of microbes, their combined genomes, and their
Susan V. Lynch, Marcus Rauch
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Genomics of the Human Gastrointestinal Microbiome
2004Abstract : We have used sequencing of targeted 16S rDNA PCR libraries and random metagenomic libraries to examine the phylogenetic and genomic diversity within the human gastrointestinal bacterial community. In one study, we used both 16S and metagenomic analysis in a study of fecal samples from three healthy human subjects.
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