Results 171 to 180 of about 80,923 (291)

The Evolutionary Trajectory and Prognostic Value of GITR+ Tregs Reprogramed by Tumor‐Intrinsic PD‐1/c‐MET Signaling in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), tumor‐intrinsic PD‐1 signaling activates the MET pathway, leading to the establishment of an immunosuppressive tumor microenvironment (TME). This MET‐driven signaling cascade promotes the selective accumulation of GITR+ regulatory T cells (Tregs), a highly immunosuppressive subset.
Jiande Han   +16 more
wiley   +1 more source

The effect of propranolol on gastrointestinal motility and permeability in patients with cirrhosis and significant portal hypertension. [PDF]

open access: yesBMC Gastroenterol
Xirouchakis E   +9 more
europepmc   +1 more source

Preoperative Immunocyte-Derived Ratios Predict Postoperative Recovery of Gastrointestinal Motility after Colorectal Cancer Surgery. [PDF]

open access: yesJ Clin Med, 2023
Firut A   +10 more
europepmc   +1 more source

Motility-modifying agents and management of disorders of gastrointestinal motility [PDF]

open access: bronze, 2000
John E. Pandolfino   +2 more
openalex   +1 more source

Human Nervous System‐Based Biohybrid Robot‐On‐A‐Chip with Sensing Function for Toxicity Screening

open access: yesAdvanced Science, EarlyView.
Human nervous system‐based biohybrid robot‐on‐a chip with eye function as sensing system in addition to brain/motor neuron/muscle functions is proposed. Upon light stimulation, the eye assembloid generates electrophysiological signals, which are transmitted through the cerebral organoid and motor neuron spheroid, inducing muscle movement.
Minkyu Shin   +6 more
wiley   +1 more source

Oral Engineered Extracellular Vesicles Based on Ion Exchange Strategy for Multipronged Management of Wilson's Disease Complicated with Reproductive Dysfunction Therapy

open access: yesAdvanced Science, EarlyView.
This study reports for the first time an oral targeted nanomedicine that conducts ion exchange through engineered Ganoderma‐derived extracellular vesicle, managing both the in‐copper and ex‐copper in a multi‐pronged approach, offering a promising therapeutic strategy for addressing WD with reproductive dysfunction.
Tingting Wang   +12 more
wiley   +1 more source

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