Results 91 to 100 of about 284,735 (262)

Nicotinamide N-Methyltransferase as Promising Tool for Management of Gastrointestinal Neoplasms. [PDF]

Biomolecules, 2022
Pozzi V, Campagna R, Sartini D, Emanuelli M.   +3 more
europepmc   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Solid pseudopapillary tumor of the pancreas mistaken for gastrointestinal stromal tumor: A case report

SAGE Open Medical Case Reports
Solid pseudopapillary epithelial neoplasms of the pancreas are rare entities, first described in 1959 by Frantz. These tumors represent less than 2% of pancreatic cancers and mainly affect young women.
Amine Achemlal, Mohamed Amine Essaoudi, Manal Jidal, Mamadou Foinke Bah, Mohammed Najih, Sidi Mohammed Bouchentouf, Sanaa Berrag, Fouad Nejjari, Tarik Adioui, Mouna Tamzaourte   +9 more
doaj   +1 more source

Gastrointestinal pathology in patients presenting with iron deficiency anaemia: A single-centre cross-sectional study

Journal of Family Medicine and Primary Care
Background: About a third of the world’s population is estimated to suffer from anaemia, and iron deficiency is expected to account for about half of all anaemia cases.
Shaik Mohammad Tahaseen, Ravi Kirti, Ramesh Kumar, Sanjay Pandey, Rajath Rao, Anjani Kumar, Rahul Arya, Tanmoy Maji, Ratnadeep Biswas   +8 more
doaj   +1 more source

Examining the impact of early enteral nutritional support on postoperative recovery in patients undergoing surgical treatment for gastrointestinal neoplasms. [PDF]

World J Gastrointest Surg, 2023
Chen Z, Hong B, He JJ, Ye QQ, Hu QY.
europepmc   +1 more source

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

Advanced Science, EarlyView.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang, Xueyan Zang, Dongli Wang, Rong Li, Hui Qian, Wenrong Xu, Jiajia Jiang, Yongmin Yan   +7 more
wiley   +1 more source

Diagnostic Accuracy of Endoscopic Ultrasonography in Selecting Patients for Endoscopic Submucosal Dissection for Early Gastrointestinal Neoplasms. [PDF]

J Clin Med, 2023
Gambitta P, Fontana P, Fanetti I, Veglia G, Vertemati M, Armellino A, Aseni P.   +6 more
europepmc   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Pathological Findings in Gastrointestinal Neoplasms and Polyps in 860 Cats and a Pilot Study on miRNA Analyses. [PDF]

Vet Sci, 2022
Kehl A, Törner K, Jordan A, Lorenz M, Schwittlick U, Conrad D, Steiger K, Schusser B, Aupperle-Lellbach H.   +8 more
europepmc   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source