Results 81 to 90 of about 686,087 (300)

Gastrointestinal Mesenchymal Neoplasms other than Gastrointestinal Stromal Tumors: Focusing on Their Molecular Aspects

, 2011
Gastrointestinal (GI) mesenchymal tumors other than gastrointestinal stromal tumor (GIST) are rare neoplasms, but they often enter the differential diagnosis of more common GI lesions.
Thomas P. Plesec
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Endoscopic submucosal dissection for gastrointestinal neoplasms

World Journal of Gastroenterology, 2008
Endoscopic submucosal dissection (ESD) is an advanced technique of therapeutic endoscopy for superficial gastrointestinal neoplasms. Three steps characterize it: injecting fluid into the submucosa to elevate the lesion, cutting the surrounding mucosa of the lesion, and dissecting the submucosa beneath the lesion. The ESD technique has rapidly permeated
Naomi, Kakushima, Mitsuhiro, Fujishiro
openaire   +2 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Paraneoplastic syndromes associated with tumors of the digestive system

Universidad Médica Pinareña, 2021
Introduction: paraneoplastic syndromes are sets of signs and symptoms affecting cancer patients, which do not depend directly on the tumor. Objective: to describe paraneoplastic syndromes associated with digestive system tumors.
Roxana Vitón-Moreno, Alain Areces-López   +1 more
doaj  

Synchronous Triple Primary Gastrointestinal Tract Malignancies: A Case Report [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Multiple primary malignant neoplasms are defined as the occurrence of two or more distinct malignant neoplasms in a single patient. However, synchronous triple primary malignant neoplasms have rarely been reported.
Hyeon Min Rim, Young Min Rah, Ju Seok Kim   +2 more
doaj   +1 more source

Management of early gastrointestinal neuroendocrine neoplasms

World Journal of Gastrointestinal Endoscopy, 2011
Neuroendocrine neoplasms (NENs) of the stomach, duodenum, appendix or rectum that are small (≤ 1 cm) and well differentiated can be considered "early" tumors, since they generally have a (very) good prognosis. In the new WHO classification of 2010, these neoplasms are called neuroendocrine tumors/ carcinoids (NETs), grade (G) 1 or 2, and distinguished ...
Hans, Scherübl, Robert T, Jensen, Guillaume, Cadiot, Ulrich, Stölzel, Günter, Klöppel   +4 more
openaire   +2 more sources

FAİLED ATTEMPT AT COLONİC PERFORATİON CLOSURE WİTH OVER THE SCOPE CLİP (OTSC): CASE REPORT [PDF]

, 2020
Giriş: Kolonoskopik perforasyon, alt gastrointestinal sistem görüntülemeleri sırasında görülebilecek en ciddi komplikasyonlardan bir tanesidir. Gastrointestinal sistem perforasyonu, hava kaçağına, gastrik veya intestinal sıvıların sızmasına, safra veya ...
Attila ÖNMEZ, İpor, Sinem, Sinem İPOR, Serkan TORUN, Önmez, Attila, Torun, Serkan   +5 more
core   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source