Results 181 to 190 of about 686,087 (300)

Three-dimensional optically cleared tissue imaging for analyzing endoscopic images of gastrointestinal neoplasms (with video). [PDF]

Dig Endosc
Nakamura K, Morishita K, Onda N, Sakai I, Matsumoto S, Tamura E, Kouyama Y, Ogawa Y, Misawa M, Hayashi T, Miyachi H, Kudo SE, Nemoto T.   +12 more
europepmc   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

Emerging Technologies in Endoscopy for Gastrointestinal Neoplasms: A Comprehensive Overview. [PDF]

Cureus
Nijjar GS, Aulakh SK, Singh R, Chandi SK.   +3 more
europepmc   +1 more source

Linked color imaging for the detection of early gastrointestinal neoplasms. [PDF]

Ther Adv Gastroenterol, 2019
Shinozaki S, Osawa H, Hayashi Y, Lefor AK, Yamamoto H.   +4 more
europepmc   +1 more source

UDC: 616.681-006:615.38:616-06 DOI: 10.2298/AOO0902025G

, 2014
Testicular neoplasms metastasizing to the retroperitoneum rarely involve the upper gastrointestinal tract. We describe an unusual case of contained small bowel perforation as a complication of chemotherapy treatment of metastatic non seminomatous germ ...
Ehab Helmy, Vojvodina Sremska Kamenica, Abdel Goad, Testicular Neoplasms Neoplasms, Germ Cell, Arch Oncol, Metastasis Retroperitoneal Neoplasms, Key Words, Embryonal Neoplasm   +8 more
core  

Micro/Nanoscale Acoustic Manipulation: From Particle Control to Autonomous Microswimmers

Advanced Science, EarlyView.
This conceptual framework illustrates acoustic technology as a multifunctional platform enabling passive particle manipulation across scales and autonomous propulsion of microswimmers. ABSTRACT Acoustic manipulation and propulsion technologies have emerged as powerful platforms for micro/nanoscale control, enabled by their non‐contact operation, label ...
Jiahui Chu, Lemin Zhang, Xu Wang, Wenzong Li, Yahua Liu   +4 more
wiley   +1 more source

Effect of Laser Auriculotherapy on Managing Neuropsychological Symptom Clusters in Patients With Gastrointestinal Neoplasms: Protocol for a Randomized Clinical Trial. [PDF]

Glob Adv Integr Med Health
de Oliveira Silva S, Silva ME, Ferreira da Fonseca J, Paolli de Paiva Oliveira Arruda Camara R, Batista da Silva MC, Pereira VDSL, Neves Dantas RA, Dantas DV, Dantas DV.   +8 more
europepmc   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

Advanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang   +9 more
wiley   +1 more source

Trends and hotspots in gastrointestinal neoplasms risk assessment: A bibliometric analysis from 1984 to 2022. [PDF]

World J Gastrointest Oncol
Fu QQ, Ma L, Niu XM, Zhao HX, Ge XH, Jin H, Yu DH, Yang S.   +7 more
europepmc   +1 more source

Ribonucleotides Amplify Mitochondrial DNA‐Driven cGAS–STING Activation via FdUMP‐ribonucleotide Hybrid Particles to Potentiate Chemoimmunotherapy

Advanced Science, EarlyView.
This work develops a metabolic sharing strategy that employs cytidine monophosphate (CMP) to competitively reprogram floxuridine (FUDR) pyrimidine metabolism in colorectal tumor cells. Elevated intracellular FdUMP induces nucleotide imbalance, drives mitochondrial DNA release and cGAS‐STING innate immune cascade activation, and potentiates robust ...
Chao Wang, Chenxuan Zhao, Yesong Yao, Zhiwen Zou, Anxin Shi, Zhuo Feng, Mingkang Yang, Yue Yu, Yang Liu, Xuehui Rui, Jinhui Wu   +10 more
wiley   +1 more source