Results 181 to 190 of about 320,222 (355)
Unmet Needs in the Field of Neuroendocrine Neoplasms of the Gastrointestinal Tract, Pancreas, and Respiratory System: Reports by the ENETS Group [PDF]
Wouter W. de Herder, Jaume Capdevila
openalex +1 more source
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu +12 more
wiley +1 more source
Introduction & Objective: 40% lymphomas are extranodal and gastrointestinal (GI) tract is the most common site. Gastrointestinal lymphomas by definition have not liver, spleen, lymph node and bone marrow involvement.
Arash Dehghan +4 more
doaj
The spatiotemporal dynamics of protein kinase diffusion govern cellular signaling and functions. Although vital for active receptors, the role of pseudokinase dynamics is unclear. Here, we use single‐molecule tracking to link faster diffusion of pseudokinase PTK7 to increased tumor cell invasion and migration.
Yaohua Li +8 more
wiley +1 more source
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang +17 more
wiley +1 more source
Routine magnifying endoscopy mode improved the diagnostic efficacy of opportunistic screening for early upper gastrointestinal neoplasms: a prospective, randomized controlled study. [PDF]
Li Y +8 more
europepmc +1 more source
Estimates of all cause mortality and cause specific mortality associated with proton pump inhibitors among US veterans: Cohort study [PDF]
Al-Aly, Ziyad +5 more
core +1 more source
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source

