Results 51 to 60 of about 138,916 (331)

Higher order organizational features can distinguish protein interaction networks of disease classes: a case study of neoplasms and neurological diseases [PDF]

open access: yesarXiv, 2022
Neoplasms (NPs) and neurological diseases and disorders (NDDs) are amongst the major classes of diseases underlying deaths of a disproportionate number of people worldwide. To determine if there exist some distinctive features in the local wiring patterns of protein interactions emerging at the onset of a disease belonging to either of these two ...
arxiv  

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Site‐specific trends in gastroenteropancreatic neuroendocrine neoplasms in Bavaria, Germany

open access: yesCancer Medicine, 2023
Introduction Neuroendocrine neoplasms (NEN) are rare and heterogeneous epithelial tumors, occurring throughout the body. For gastroenteropancreatic (GEP)‐NEN, rising incidence rates were reported for the last decades, with underlying causes remaining ...
Nina Grundmann   +5 more
doaj   +1 more source

A Hierarchical Transformer Encoder to Improve Entire Neoplasm Segmentation on Whole Slide Image of Hepatocellular Carcinoma [PDF]

open access: yesarXiv, 2023
In digital histopathology, entire neoplasm segmentation on Whole Slide Image (WSI) of Hepatocellular Carcinoma (HCC) plays an important role, especially as a preprocessing filter to automatically exclude healthy tissue, in histological molecular correlations mining and other downstream histopathological tasks.
arxiv  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Epidemiology of gastrointestinal proliferative neoplastic-like lesions and tumors in dogs and cats: a retrospective study in two Romanian reference laboratories

open access: yesCluj Veterinary Journal
Gastrointestinal neoplasms are rare in dogs and cats, primarily comprising adenocarcinomas, lymphomas, leiomyomas, leiomyosarcomas, and gastrointestinal stromal tumors (GISTs). In the current literature  epidemiological data  are scars. The aim of  this
Andrada Negoescu   +4 more
doaj   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

Stromal tumor of the lesser omentum: a case report

open access: yesThe Pan African Medical Journal, 2014
Gastrointestinal stromal tumors (GISTs) represent the majority of primary non-epithelial neoplasms of the digestive tract, most frequently expressing the KIT protein detected by immunohistochemical staining for the CD117 antigen.
Hossam Behammane   +6 more
doaj   +1 more source

Emergency surgery for gastrointestinal cancer: A nationwide study in Japan based on the National Clinical Database

open access: yesAnnals of Gastroenterological Surgery, 2020
Background Emergency gastrointestinal surgery, although rare, is known for its high mortality and morbidity. However, the risks of emergency surgery for gastrointestinal cancer have not been investigated in depth.
Nobuaki Hoshino   +11 more
doaj   +1 more source

Rapunzel syndrome [PDF]

open access: yesVojnosanitetski Pregled, 2012
Introduction. Trichobezoars are foreign bodies in gastrointestinal tract, composed of hair. They occur mainly in children and adolescents suffering from trichotillophagia.
Petrović Gordana   +5 more
doaj   +1 more source

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