Minimal residual disease in solid tumors: Clinical applications and future directions
Abstract Minimal residual disease (MRD) refers to the presence of residual cancer cells or tumor‐derived fragments that persist after treatment and remain undetectable by conventional imaging or protein‐based assays. Circulating tumor DNA (ctDNA) has emerged as a dynamic biomarker for MRD detection.
Theresa Abdo +8 more
wiley +1 more source
Beyond bacterial defences: the role of lysozyme in cancer
Lysozyme (LYZ) is a multi‐functional secreted factor that encompasses both antibacterial and immunomodulatory functions. Emerging evidence highlights its complex role in tumour progression by directly influencing tumour cells and modulating the immune microenvironment.
Lei Wang +4 more
wiley +1 more source
Hidden risk factors for recurrence of jejunoileal Gastrointestinal stromal tumors with low NIH classification: implications for surveillance and adjuvant therapy. [PDF]
Sun X +7 more
europepmc +1 more source
Cytologic and Histologic Findings of Extrapleural Solitary Fibrous Tumor: Report of Two Cases
ABSTRACT Solitary fibrous tumors (SFT) are a rare neoplasm of mesenchymal origin. SFT was previously described primarily in the pleura and meninges; however, extrapleural and extra‐meningeal SFT have been reported in almost every anatomic site and account for up to 40% of cases.
Michael Tyler +4 more
wiley +1 more source
Hepatic hemangiomas mimicking gastrointestinal stromal tumors: A case report. [PDF]
Wang JZ, Chen H.
europepmc +1 more source
Ricinus Communis: Nutritional Importance, Health Benefits, and Industrial Applications
The current paper summarizes the nutritional composition, phytochemistry, health benefits, safety studies, and applications of castor beans and their oil. Moreover, the diverse bioactive compounds, including saponins, emodins, terpenoids, anthraquinones, flavonoids, steroids, and alkaloids, exhibit therapeutic properties such as antioxidant, anticancer,
Hassan Raza +13 more
wiley +1 more source
Molecular Mechanisms and Clinical Implications of <i>Fibroblast Growth Factor Receptor 2</i> Signaling in Gastrointestinal Stromal Tumors. [PDF]
Hong Y, Wang X, Shou C, Liu X.
europepmc +1 more source
ABSTRACT Extracellular vesicles (EVs) released from tissues can be found in human biofluids. EVs reflect the phenotypic state of their cell of origin, carrying informative molecular biomarkers within and between tissues, and represent a promising target for liquid biopsy.
Biancamaria Pierri +5 more
wiley +1 more source
Variation in mitotic counting and risk classification practices for gastrointestinal stromal tumors: a survey of pathologists in South Korea. [PDF]
Song IH, Ahn S, Jo JH, Park YS.
europepmc +1 more source
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source

