Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley +1 more source
Pediatric Functional Constipation Gastrointestinal Symptom Profile Compared With Healthy Controls
Patient-reported outcomes are necessary to evaluate the gastrointestinal symptom profile of patients with functional constipation. Study objectives were to compare the gastrointestinal symptom profile of pediatric patients with functional constipation ...
Pediatric Quality of Life Inventory Gastrointestinal Symptoms Module Testing Study Consortium +8 more
core +1 more source
SARS-CoV-2 Variant-Specific Gastrointestinal Symptoms of COVID-19: 2023 Update
The gastrointestinal (GI) tract may be a significant entrance or interaction site for SARS-CoV-2; therefore, the gut mucosal immune system participates in virus interaction as a first-line physical and immunological defense, leading to GI involvement and
Snezhina Lazova +25 more
core +1 more source
Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich +35 more
wiley +1 more source
Antidepressants and gastrointestinal symptoms in the general Dutch adult population
Contains fulltext : 136013.pdf (Publisher’s version ) (Closed access)BACKGROUND: Gastrointestinal symptoms are frequently reported adverse effects of antidepressants, but antidepressants are also a treatment modality in functional ...
Eikendal, T. +8 more
core +1 more source
Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa +3 more
wiley +1 more source
Clinical changes in the gastrointestinal system as a result of the influence of Covid-19 [PDF]
Research shows that, in addition to primarily presenting as a lung infection, coronavirus infections have been re-established to have significant extrapulmonary complications that affect multiple organ systems, including the gastrointestinal tract ...
Nurbayev Farmon
doaj +1 more source
Dietary fibre in the management of gastrointestinal symptoms
Dietary fibre in the management of gastrointestinal ...
Smith, Graeme D, Graeme D Smith
core +1 more source
Gastrointestinal symptoms in abused nonpatient women
Background Severely abused nonpatient women report a high number of gastrointestinal (GI) symptoms and GI syndromes. Little is known about whether the abuse‒symptom relationship varies across different life, social, and community conditions. Objective To
Nadia Pallotta +6 more
doaj +1 more source
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source

