Results 211 to 220 of about 1,198,615 (311)

Practical Computational Exploration of Chemical Reaction Space: Assessing the Chemical Stability of Active Pharmaceutical Ingredients Under Acidic Conditions

Angewandte Chemie, EarlyView.
Metadynamics simulations drive automated reaction exploration of acid‐catalysed drug degradation, generating a network spanning 1720 species and 2471 elementary steps. QM‐based filtering reduces the network to eight candidate pathways for rigorous DFT refinement and microkinetic modelling.
Julius Seumer, Maria Harris Rasmussen, Oriana Brea, Mikko Muuronen, Andreas H. Göller, Jan H. Jensen   +5 more
wiley   +2 more sources

Comprehensive insights into the roles of eosinophils in the mucosal immunity of gastrointestinal tract: defenders, destructors, and modulators. [PDF]

Front Immunol
Chen X, Li K, Jin X, He X, Du Z, Liu S, Jiang S, Ou C, Li J, Li J.   +9 more
europepmc   +1 more source

Therapy for Myhre Syndrome: Goals, Misconceptions, and Current Agents

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre Syndrome (MYHRS, MIM #139210) is a rare, multisystem connective tissue disorder caused by recurrent heterozygous gain‐of‐function pathogenic variants in the SMAD4 gene, a key player in TGF‐β signaling and a regulator of extracellular matrix homeostasis.
Alessandro De Falco, Alfonso Manuel D'Alessio, Nicola Brunetti‐Pierri   +2 more
wiley   +1 more source

Clinical features of hereditary angioedema involving the gastrointestinal tract: A retrospective analysis. [PDF]

World Allergy Organ J
Ma H, Zheng D, Wang Y, Tian C, Huang Z, Xiong S, Ke Y, Mao R, He Y, Chen M, Li X, Chen B.   +11 more
europepmc   +1 more source

Anaemia and the Gastrointestinal Tract [PDF]

BMJ, 1938
openaire   +2 more sources

The potency of native postbiotics and paraprobiotics in modulating inflammation by affecting the gut–kidney axis

Animal Models and Experimental Medicine, EarlyView.
Native postbiotics and paraprobiotics derived from Lactobacillus and Bifidobacterium strains were administered to dextran sulfate sodium–treated C57BL/6 mice to evaluate their impact on kidney inflammation via the gut–kidney axis. Histological analysis and quantitative polymerase chain reaction of autophagy‐related genes (atg5, atg7, atg12, atg13 ...
Fatemeh Haririzadeh Jouriani, Mahnaz Torfeh, Fatemeh Ashrafian, Niloofar Rezaie, Mohsen Mohammadi, Shadi Aghamohammad, Mahdi Rohani   +6 more
wiley   +1 more source

Alteration of Acid-Binding Capacity of Various Nursery Pig Diets and Its Influence on Properties of Digesta Along the Gastrointestinal Tract. [PDF]

J Anim Physiol Anim Nutr (Berl)
Choi H, Kim SW.
europepmc   +1 more source

Perforation of the gastrointestinal tract by a ventriculoperitoneal shunt catheter with anal exteriorization in an adult patient: case report. [PDF]

J Surg Case Rep
da Silva Correia VM, Muller JVC, Barros HC, Nakata MVYM, Delis I, Costa PF.   +5 more
europepmc   +1 more source

Dynamic changes in the plasmidome and resistome in the gastrointestinal tract of chickens. [PDF]

Microbiol Spectr
Rysava M, Stredanska K, Schwarzerova J, Jakubickova M, Cejkova D, Aytan-Aktug D, Otani S, Dolejska M, Palkovicova J.   +8 more
europepmc   +1 more source

Somatostatin in Aging: Correlations with Selected Central Nervous System and Gastrointestinal Tract Diseases. [PDF]

Int J Mol Sci
Kasprzak A.
europepmc   +1 more source