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Mesoderm and endoderm internalization in the Xenopus gastrula
Current Topics in Developmental Biology, 2020Mesoderm and endoderm internalization in the Xenopus embryo are based on a number of region-specific morphogenetic processes that co-act in the vegetal half of the gastrula. In the multilayered wall surrounding the blastocoel, the apical layer engages in bottle cell formation and associated invagination and involution movements, and in cell ...
Rudolf Winklbauer
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Mesoderm migration in the Xenopus gastrula
The International Journal of Developmental Biology, 1996During Xenopus gastrulation, the mesoderm involutes at the blastopore lip and moves on the inner surface of the BCR toward the animal pole of the embryo. Active cell migration is involved in this mesoderm translocation. In vitro, mesoderm cells migrate non-persistently and intermittently by extending and retracting multiple lamellipodia, which pull the
R, Winklbauer +3 more
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Gastrula organiser and embryonic patterning in the mouse
Seminars in Cell & Developmental Biology, 2004Embryonic patterning of the mouse during gastrulation and early organogenesis engenders the specification of anterior versus posterior structures and body laterality by the interaction of signalling and modulating activities. A group of cells in the mouse gastrula, characterised by the expression of a repertoire of "organiser" genes, acts as a source ...
Lorraine, Robb, Patrick P L, Tam
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Cell migration in the Xenopus gastrula
WIREs Developmental Biology, 2018Xenopus gastrulation movements are in large part based on the rearrangement of cells by differential cell‐on‐cell migration within multilayered tissues. Different patterns of migration‐based cell intercalation drive endoderm and mesoderm internalization and their positioning along their prospective body axes.
Yunyun, Huang, Rudolf, Winklbauer
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Domains of movement in the zebrafish gastrula
Seminars in Developmental Biology, 1994Abstract The mechanisms controlling cell movements during vertebrate gastrulation are not known. Studies using the zebrafish embryo show promise at identifying these mechanisms, combining an embryo that is accessible and optically clear with mutations that affect early development.
Donald A. Kane, Rachel M. Warga
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Directional mesoderm cell migration in the Xenopus gastrula
Developmental Biology, 1991The movement of the dorsal mesoderm across the blastocoel roof of the Xenopus gastrula is examined. We show that different parts of the mesoderm which can be distinguished by their morphogenetic behavior in the embryo are all able to migrate independently on the inner surface of the blastocoel roof.
Winklbauer, R. ; https://orcid.org/0000-0002-0628-0897 +1 more
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Extracellular Materials and Determination of Neuroectoblast in Amphibian Gastrula
Experimental Cell Biology, 2008The biological activity of the extracellular material (ECM) located in the dorsal and ventral regions of Bufo arenarum is assayed. Ectoblast cells were isolated and cultured with ECM taken from the embryonal regions. The epiblastic cells treated with dorsal ECM, mainly located at the interphase between the invaginating blastoporal lip and the overlying
S S, Sánchez, F D, Barbieri
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Glycosaminoglycan synthesis in the chick gastrula
Developmental Biology, 1976Explanted definitive primitive streak to four somite chick embryos were labeled with [H3]glucosamine or S35O4 and the glycosaminoglycans were isolated and characterized. On the basis of susceptibility to Streptomyces hyaluronidase, which specifically degrades hyaluronic acid, hyaluronic acid is the major glycosaminoglycan produced by these embryos (at ...
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Building the mouse gastrula: signals, asymmetry and lineages
Current Opinion in Genetics & Development, 2006The mouse embryo is built by assembling the progenitors of various tissue types into a body plan. Early postimplantation development involves the establishment of anatomical asymmetries and regionalized gene expression in the conceptus, the specification of tissue lineages, and the coordination of cell movement for correct positioning of the lineage ...
Patrick P L, Tam +2 more
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