Results 101 to 110 of about 150,035 (257)

Cutting Edge : Failure of Antigen-Specific CD4+ T Cell Recruitment to the Kidney during Systemic Candidiasis [PDF]

, 2014
Copyright © 2014 The Authors. Acknowledgments We thank E. Bolton and H. Bagavant for reagents and advice. We also acknowledge the staff of the Medical Research Facility at the University of Aberdeen for care of the animals used in this study.
Brown, Gordon D, Drummond, Rebecca A, Kaplan, Daniel H, Reid, Delyth M, Wallace, Carol, Way, Sing Sing   +5 more
core   +2 more sources

Beyond the chaos: How architecture structures tumour biology

The FEBS Journal, EarlyView.
Tissue architecture shapes tumour initiation and progression through multiple interconnected layers continuously remodelled over time. This review outlines how physical forces, biochemical cues, cellular niches and systemic influences contribute to tumour evolution.
Lea Dörner, Catrin Lutz, Stefan Prekovic, Hendrik A. Messal   +3 more
wiley   +1 more source

The evolution of protostome GATA factors: Molecular phylogenetics, synteny, and intron/exon structure reveal orthologous relationships [PDF]

, 2008
Background Invertebrate and vertebrate GATA transcription factors play important roles in ectoderm and mesendoderm development, as well as in cardiovascular and blood cell fate specification.
William Q Gillis, Bruce A Bowerman, Stephan Q Schneider   +2 more
core   +2 more sources

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

The FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo, Bastien Morlet, Luc Negroni, Orsolya Mózner, Balázs Sarkadi, Gilles Travé, Gergo Gogl   +6 more
wiley   +1 more source

Unraveling Heterogeneity in Epithelial Cell Fates of the Mammary Gland and Breast Cancer. [PDF]

, 2019
Fluidity in cell fate or heterogeneity in cell identity is an interesting cell biological phenomenon, which at the same time poses a significant obstacle for cancer therapy.
Doh, Hanna, Kessenbrock, Kai, Roose, Jeroen P, Samocha, Alexandr   +3 more
core   +1 more source

Immunophenotypic assessment of pure embryonal carcinoma and yolk sac tumour suggests that reprogramming to non‐seminoma occurs outside the spermatogonial niche

Histopathology, EarlyView.
Immunohistochemical analysis of transcription factors in GCNIS associated with pure EC and YST suggests that reprogramming to non‐seminoma occurs outside the spermatogonial niche. In these tumors, reprogramming may occur immediately upon invasion of the stroma or within seminiferous tubules but outside the spermatogonial niche (i.e., in intratubular ...
Daisy Maharjan, Květoslava Michalová, Joao Lobo, Jennifer Gordetsky, Fiona MacLean, Ankur R Sangoi, Daniel Berney, Chia‐Sui Kao, Costantino Ricci, Adeboye O Osunkoya, Maria Rosaria Raspollini, Geert JLH van Leenders, Muhammad T Idrees, Lee Ann Baldridge, Thomas M Ulbright, Andres M Acosta   +15 more
wiley   +1 more source

Capa Física de la 5ª Generación de Comunicaciones Móviles [PDF]

, 2018
Los sistemas de comunicaciones móviles de 5ª Generación no serán desplegados hasta el año 2020, pero su desarrollo comenzó hace ya varios años. Múltiples avances tecnológicos serán necesarios para alcanzar los objetivos propuestos en esta nueva ...
Gata Romero, José Manuel
core  

The transcription factors TaABI4 and TaNAC‐A1 fine‐tune TaCYP94‐A1 transcription to modulate seed dormancy in wheat

Journal of Integrative Plant Biology, EarlyView.
A module involving the transcription factors TaABI4 and TaNAC‐A1, and the cytochrome P450 TaCYP94‐A1 precisely regulates seed dormancy levels through plant hormone crosstalk, providing targets for improving resistance to pre‐harvest sprouting in wheat.
Litian Zhang, Yuhui Fang, Yunfei Zhou, Xianlai Nie, Shujun Cao, Wei Gao, Yu Wang, Lianghua Dai, Lin Ye, Jie Lu, Chuanxi Ma, Cheng Chang, Haiping Zhang   +12 more
wiley   +1 more source

Acute Exudative Diffuse Proliferative Glomerulonephritis in A Patient with Type 2 Diabetes Mellitus

Turkish Journal of Nephrology, 2019
The prevalence of non-diabetic renal disease varies widely from 12 to 45% among type 2 diabetic patients proven by renal biopsy performed. We describe a case of a patient with type 2 diabetes mellitus and acute diffuse proliferative exudative ...
Alper KIRKPANTUR, Gürkan ÇELEBİ, Tayfun EYİLETEN, Mahmut İlker YILMAZ, Kayser ÇAĞLAR, Yusuf OĞUZ, Ayhan ÖZCAN, Abdülgaffar VURAL, Müjdat YENİCESU   +8 more
doaj  

Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa

BMC Gastroenterology, 2008
Background Human gastrointestinal mucosa regenerates vigorously throughout life, but the factors controlling cell fate in mature mucosa are poorly understood.
Mäki Markku, Lindfors Katri, Westerholm-Ormio Mia, Haveri Hanna, Savilahti Erkki, Andersson Leif C, Heikinheimo Markku   +6 more
doaj   +1 more source