Results 131 to 140 of about 150,035 (257)
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
MedComm – Oncology, Volume 5, Issue 2, June 2026.Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
Histopathology, Volume 88, Issue 7, Page 1315-1323, June 2026.PAX8 expression in urothelial carcinoma was investigated in 101 consecutive transurethral resections of the urinary bladder. PAX8 was positive in 10% of cases, with targeted molecular testing of these cases revealing universal TERT promoter mutations and frequent alterations in TSC1, NOTCH1 and WT1. Aims PAX8 immunohistochemistry (IHC) is often used to
Sarah Mae Lammert +5 more
wiley +1 more source
Turkish Journal of Nephrology, 2019 Assessment of dry weight in hemodialysis patients is essential. Intravascular hypervolemia increases the levels of digitalis-like immunoreactive substance (DLIS), atrial natriuretic peptide (ANP) and it alters echocardiographic parameters.
T. Rıfkı EVRENKAYA +8 more
doaj
GATA2 Mutations Predict Poor Prognosis in Transplanted Myeloid Neoplasms
Cancer Medicine, Volume 15, Issue 5, May 2026.ABSTRACT Background GATA binding protein 2 (GATA2) plays a crucial role in the differentiation, proliferation, and maintenance of hematopoietic stem cells (HSCs). GATA2 mutations have been identified in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), but the impact of somatic GATA2 mutations on prognosis remains controversial ...
Xian Zhang +8 more
wiley +1 more source
Bilateral Renal Infarct in A Patient with Atrial Fibrillation
Turkish Journal of Nephrology, 2019 Renal infarction is an uncommon diagnosis with an incidence of about 0.007% of emergency department admissions. It is often mimicked by other more common diseases such as urolithiasis or other abdominal lesions at clinical presentation.
Alper KIRKPANTUR +6 more
doaj
Metastasis of Hepatocellular Carcinoma to the Urinary Bladder: A Case Report and Literature Review
IJU Case Reports, Volume 9, Issue 3, May 2026.ABSTRACT Introduction Although secondary bladder tumors from distant metastases are rare, those originating from hepatocellular carcinoma are particularly uncommon, with only a few cases reported to date. Case Presentation An 81 year old male with hepatocellular carcinoma developed a rapidly growing 23 mm‐sized bladder tumor during systemic therapy ...
Eri Fukagawa +6 more
wiley +1 more source
Innate Lymphoid Cells in Tissue Homeostasis and Diseases
MedComm, Volume 7, Issue 5, May 2026.Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan +7 more
wiley +1 more source
Medicinal Research Reviews, Volume 46, Issue 3, Page 672-712, May 2026.ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi +6 more
wiley +1 more source
The Hemoprotein Hhy1 Promotes Heme‐Dependent Catalase Activity of Ctt1
Molecular Microbiology, Volume 125, Issue 5, Page 389-411, May 2026.A Schizosaccharomyces pombe strain deficient in heme (hem1Δ) and siderophore (Fc) biosynthesis, as well as high‐affinity iron (Fe) uptake (blue), was used to uncover the hemoprotein Hhy1 that promotes the heme‐dependent activity of the catalase Ctt1. In contrast, hhy1Δ cells exhibit reduced Ctt1 activity and increased sensitivity to oxidative stress ...
Tobias Vahsen +3 more
wiley +1 more source
Molecular Plant Pathology, Volume 27, Issue 5, May 2026.SDE4250 suppressed 26S proteasome activity by targeting CsRPN10 and enhancing its degradation via the proteasome pathway. This impairment of proteasome function subsequently attenuates SA‐mediated defence responses, thereby increasing citrus susceptibility to promote CLas infection.
Yalin Mei +7 more
wiley +1 more source