Results 71 to 80 of about 150,035 (257)
GATA Factor-Dependent Positive-Feedback Circuit in Acute Myeloid Leukemia Cells
Cell Reports, 2016 The master regulatory transcription factor GATA-2 triggers hematopoietic stem and progenitor cell generation. GATA2 haploinsufficiency is implicated in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), and GATA2 overexpression portends a ...
Koichi R. Katsumura +4 more
doaj +1 more source
GATA-1 deficiency rescues trabecular but not cortical bone in OPG deficient mice [PDF]
, 2014 GATA-1(low/low) mice have an increase in megakaryocytes (MKs) and trabecular bone. The latter is thought to result from MKs directly stimulating osteoblastic bone formation while simultaneously inhibiting osteoclastogenesis.
Cheng, Ying-Hua +6 more
core +1 more source
GATA Transcription Factors and Cancer [PDF]
Genes & Cancer, 2010 It has been almost a quarter century since it was first appreciated that a class of oncogenes contained in rapidly transforming avian retroviruses encoded DNA-binding transcription factors. As with other oncogenes, genetic recombination with the viral genome led to their overexpression or functional alteration.
Rena, Zheng, Gerd A, Blobel
openaire +2 more sources
Epigenetic Regulation of Immune Dysfunction in Chronic Prostatitis/Chronic Pelvic Pain Syndrome
The Prostate, EarlyView.ABSTRACT Background Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent and debilitating condition with unclear etiology. Increasing evidence implicates immune dysregulation, yet the molecular mechanisms underlying impaired immune regulation remain poorly defined. This study investigated the role of altered immune responses within
Praveen Thumbikat +8 more
wiley +1 more source
Psychiatry and Clinical Psychopharmacology, 2021 There is ardent dispute about the role of trace elements in brain tissues. Investigations have shown that cellular functions, metabolism and behavior are influenced by, and sometimes even dependent on the peresence o f trace elements.
Mesut ÇETİN +4 more
doaj
Cognitive functions in bipolar manic and remitted episodes: a longitudinal study
Psychiatry and Behavioral Sciences, 2015 Objective: Patients with bipolar disorder often suffer from persistent cognitive impairments. However, it is not described fully that these impairments are associated with episodes of the disorder.
Nakşidil Yazıhan +3 more
doaj +1 more source
Lingua Montenegrina, 2016 U radu je temeljem podataka prikupljenih u prvom redu terenskim istraživanjem prikazana toponimija naselja Gata koje se nalazi u omiškom zaleđu, južno od Splita. Podatci su uspoređeni s katastarskim knjigama i dostupnim zemljovidima te toponomastički obrađeni. Nude se povijesni i geografski okviri naselja te osnovne karakteristike govora Gata. Obrađeno
Lozić Knezović, Katarina +1 more
openaire +2 more sources
Environmental Toxicology, EarlyView.ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho +7 more
wiley +1 more source
A theory of international conflict management and sanctioning [PDF]
In this paper we analyze sanctioning policies in international law. We develop a model of international military conflict where the conflicting countries can be a target of international sanctions.
Joao E. Gata, Nuno Garoupa
core
A gene regulatory network armature for T lymphocyte specification [PDF]
, 2008 Choice of a T lymphoid fate by hematopoietic progenitor cells depends on sustained Notch–Delta signaling combined with tightly regulated activities of multiple transcription factors. To dissect the regulatory network connections that mediate this process,
Bolouri, Hamid +7 more
core +2 more sources