Results 121 to 130 of about 294,757 (224)

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao   +12 more
wiley   +1 more source

Progress and Perspectives in 2D Piezoelectric Materials for Piezotronics and Piezo‐Phototronics

open access: yesAdvanced Science, EarlyView.
This review examines advancements in 2D materials, focusing on their applications in piezotronics and piezo‐phototronics. It discusses key materials like TMDs, h‐BN, and phosphorene, highlighting their unique mechanical, electronic, and optical properties.
Fengyi Pang   +6 more
wiley   +1 more source

High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection

open access: yesAdvanced Science, EarlyView.
Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni   +15 more
wiley   +1 more source

Key Connectomes and Synaptic‐Compartment‐Specific Risk Genes Drive Pathological α‐Synuclein Spreading

open access: yesAdvanced Science, EarlyView.
Utilizing a stereotaxic injection mouse model and a novel mathematical approach, this study uncovers key subnetworks that drive pathological α‐synuclein (α‐Syn) progression in Parkinson's disease (PD). Remarkably, just 2% of the strongest connections in the connectome are sufficient to predict its spread.
Yuanxi Li   +16 more
wiley   +1 more source

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