Results 91 to 100 of about 105,914 (269)
Advanced Science, EarlyView.Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
Advanced Science, EarlyView.To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo +3 more
wiley +1 more source
Iconarp International Journal of Architecture and Planning, 2015 Gated communities are the new forms of residential settlements, which emerged as a response to changing urban dynamics, becoming increasingly common across the world.
Emine Yıldız Kuyrukçu +2 more
doaj +2 more sources
Advanced Science, EarlyView.ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao +14 more
wiley +1 more source
Gaining access into gated communities: Reflections from a fieldwork in Istanbul, Turkey [PDF]
, 2014 In this piece, Basak Tanulku shares her experiences of conducting fieldwork in gated communities in Istanbul, Turkey for her PhD research. She explains how she decided to work on gated communities, and discusses the problems arising due to difficulties ...
Tanulku, Basak
core
Decoding Trap States in Working 2D Perovskite Multi‐Functional Devices
Advanced Science, EarlyView.Illustration of the photoluminescence spectrum and energy‐level landscape governing trap‐mediated carrier dynamics in 2D F‐PEAI photodetectors. A novel approach capturing dynamic trap occupation and retrapping in devices under operating conditions, directly links defect energetics to carrier transport and enhanced photoresponse in multifunctional ...
Ioannis Leontis +8 more
wiley +1 more source
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Collective housing as a good way to reduce city fragmentation [PDF]
, 2014 Today the study of the fragmentation represents an important occasion to meditate on the city and on the evolution of the relational strategies of settlements.
Bertolino, N, +3 more
core
Neural Fields for Highly Accelerated 2D Cine Phase Contrast MRI
Advanced Science, EarlyView.ABSTRACT 2D cine phase contrast (CPC) MRI provides quantitative information on blood velocity and flow within the human vasculature. However, data acquisition is time‐consuming, motivating the reconstruction of the velocity field from undersampled measurements to reduce scan times. In this work, neural fields are proposed as a continuous spatiotemporal
Pablo Arratia +7 more
wiley +1 more source
No. 04: The Urban Food System of Kingston, Jamaica [PDF]
, 2017 Kingston is a colonial city and, like the country of Jamaica more generally, was the product of early mercantilism moulded by colonialism, sugar plantations and slavery.
Ferguson, Therese +4 more
core +1 more source