Results 1 to 10 of about 1,011,946 (298)

Functional crosstalk between the cohesin loader and chromatin remodelers

open access: yesNature Communications, 2022
Chromatin remodelers direct the cohesin loader to nucleosome depleted regions where cohesin accesses chromosomes. Muñoz et al. now show that the cohesin loader in turn is a biochemical activator of a chromatin remodeler, helping to clear ...
Sofía Muñoz   +5 more
doaj   +1 more source

A Brownian ratchet model for DNA loop extrusion by the cohesin complex

open access: yeseLife, 2021
The cohesin complex topologically encircles DNA to promote sister chromatid cohesion. Alternatively, cohesin extrudes DNA loops, thought to reflect chromatin domain formation. Here, we propose a structure-based model explaining both activities.
Torahiko L Higashi   +4 more
doaj   +1 more source

A role for condensin in mediating transcriptional adaptation to environmental stimuli

open access: yesLife Science Alliance, 2021
Fast conditional depletion of the chromosomal condensin complex from budding yeast cells reveals roles in transcriptional regulation, especially during the establishment of new gene expression patterns.
Lucy Lancaster   +3 more
doaj   +1 more source

Reproductive Isolation Between Taxonomically Controversial Forms of the Gray Voles (Microtus, Rodentia; Arvicolinae): Cytological Mechanisms and Taxonomical Implications

open access: yesFrontiers in Genetics, 2021
The formation of hybrid sterility is an important stage of speciation. The voles of the genus Microtus, which is the most speciose genus of rodents, provide a good model for studying the cytological mechanisms of hybrid sterility.
Tatiana I. Bikchurina   +7 more
doaj   +1 more source

Prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes

open access: yesNature Communications, 2020
Oocyte meiosis must achieve spindle bipolarization without predefined spatial cues. Yoshida et al. demonstrate that spindle bipolarization during meiosis I in mouse oocytes requires kinetochores to prevent chromosome segregation errors, a phenomenon that
Shuhei Yoshida   +12 more
doaj   +1 more source

The large cytoplasmic volume of oocyte

open access: yesThe Journal of Reproduction and Development, 2022
The study of the size of cells and organelles has a long history, dating back to the 1600s when cells were defined. In particular, various methods have elucidated the size of the nucleus and the mitotic spindle in several species.
Hirohisa KYOGOKU, Tomoya S KITAJIMA
doaj   +1 more source

The structural heredity demonstration and its effect on the properties of hot-rolled tubing stocks of various diameters [PDF]

open access: yesМеталознавство та обробка металів, 2020
The number of redistributions decreasing tendency in the production of rolled products, with all the positive economic effect, leads to the fact that the metal is subjected to a less intense deformation effect at low temperatures.
Balakhanova T. V.   +2 more
doaj   +1 more source

Segregation in networks [PDF]

open access: yesJournal of Economic Behavior & Organization, 2007
Schelling (1969, 1971a,b, 1978) considered a simple model with individual agents who only care about the types of people living in their own local neighborhood. The spatial structure was represented by a one- or two-dimensional lattice. Schelling showed that an integrated society will generally unravel into a rather segregated one even though no ...
GIORGIO FAGIOLO   +2 more
openaire   +10 more sources

Cell-Cycle Regulation of Dynamic Chromosome Association of the Condensin Complex

open access: yesCell Reports, 2018
Summary: Eukaryotic cells inherit their genomes in the form of chromosomes, which are formed from the compaction of interphase chromatin by the condensin complex. Condensin is a member of the structural maintenance of chromosomes (SMC) family of ATPases,
Rahul Thadani   +4 more
doaj   +1 more source

Fission yeast condensin contributes to interphase chromatin organization and prevents transcription-coupled DNA damage

open access: yesGenome Biology, 2020
Background Structural maintenance of chromosomes (SMC) complexes are central organizers of chromatin architecture throughout the cell cycle. The SMC family member condensin is best known for establishing long-range chromatin interactions in mitosis ...
Yasutaka Kakui   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy