Results 31 to 40 of about 1,011,946 (298)

Protocol for studying topological DNA interactions by purified fission yeast condensin

STAR Protocols
Summary: To understand the transition from interphase chromatin into well-shaped chromosomes during cell divisions, we need to understand the biochemical activities of the contributing proteins.
Minzhe Tang, Frank Uhlmann
doaj   +1 more source

Intra-urban inequalities during rapid development: space egalitarianism in Tokyo between 1955-1975

International Journal of Urban Sustainable Development, 2021
This paper demonstrates empirically that Tokyo’s rapid post-war growth coincided with decreasing intra-urban inequalities in the special ward area, both in terms of private and public living standards.
Benjamin Bansal
doaj   +1 more source

Taking the Social out of Social Housing? Recent Developments, Current Tendencies, and Future Challenges to the Danish Social Housing Model

Tidsskrift for boligforskning, 2023
The Danish social housing sector is not actually a social housing sector in the sense that it supplies housing only to the socially deprived. Rather, the sector is open to everyone who puts their name on a waiting list.
Rikke Skovgaard Nielsen, Lene Wiell Nordberg, Hans Thor Andersen   +2 more
doaj   +1 more source

Female participation increases and gender segregation. ESRI WP564, May 2017 [PDF]

, 2017
This article examines the impact of a large increase in female participation on occupational segregation. Increases in female participation may decrease occupational segregation if women enter male dominated sectors but may increase segregation if they ...
Keane, Claire, Russell, Helen, Smyth, Emer   +2 more
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

High chrome cast iron for mineral processing and conveying equipment parts

Литьë и металлургия, 2022
The main reasons for the formation of microand macrocracks and other defects in waterjet castings, which significantly reduce their service life, are analyzed.
A. S. Gudenko, N. S. Gushchin, E. A. Makarova, N. V. Parshikova   +3 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Kif11-haploinsufficient oocytes reveal spatially differential requirements for chromosome biorientation

EMBO Reports
Bipolar spindle assembly and chromosome biorientation are prerequisites for chromosome segregation during cell division. The kinesin motor KIF11 (also widely known as Eg5) drives spindle bipolarization by sliding antiparallel microtubules bidirectionally,
Tappei Mishina, Aurélien Courtois, Shuhei Yoshida, Kohei Asai, Hiroshi Kiyonari, Tomoya S Kitajima   +5 more
doaj   +1 more source

Evidence of substrate control of Cdk phosphorylation during the budding yeast cell cycle

Cell Reports
Summary: A series of sequential events orchestrates cell growth and division, set in motion by cyclin-dependent kinases (Cdks). In the “qualitative model” for Cdk control, order is achieved by cell cycle stage-specific cyclins.
Luca Takacs, Lina Gerontogianni, Kimberly Quililan, Helen Flynn, Frank Uhlmann   +4 more
doaj   +1 more source