Results 191 to 200 of about 203,537 (274)

Increased intervals in enzyme replacement therapy for stable type 1 Gaucher disease: A non‐inferiority sequential trial emulation

open access: yesJournal of Internal Medicine, Volume 299, Issue 5, Page 604-614, May 2026.
Abstract Objective To compare the efficacy and safety of extended interval (Q3–4W) enzyme replacement therapy (ERT) versus standard biweekly (Q2W) ERT in clinically stable type 1 Gaucher disease (GD) patients. Methods We emulated a target trial with a sequential trial design, using data from the French Gaucher Disease Registry.
Maxime Beydon   +31 more
wiley   +1 more source

Clinical Exome Sequencing in Unexplained Hyperferritinemia Reveals Digenic and Oligogenic Inheritance Beyond Iron Homeostasis

open access: yesLiver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background and Aims Hyperferritinemia encompasses heterogeneous genetic etiologies beyond HFE‐related hemochromatosis. Current guidelines recommend testing for rare hemochromatosis genes, yet no consensus exists on comprehensive genomic approaches.
Paul Morel   +11 more
wiley   +1 more source

Goutte tophacée ulcéreuse. [PDF]

open access: yesCMAJ
Gupta S, Le Roux A, Madrazo L.
europepmc   +1 more source

Why Paternalism Is Wrong (When It Is Wrong)

open access: yesPhilosophy and Phenomenological Research, Volume 112, Issue 3, Page 578-593, May 2026.
ABSTRACT This paper proposes a novel reinterpretation of the familiar, if inchoate, thought that paternalism offends against an ideal of personal sovereignty. The central idea is that (competent) persons have a particular kind of normative power. Just as each of us has the right to control how others are permitted to use our bodies or property, we each
Jonathan Parry
wiley   +1 more source

A Computational Modeling of ADLumin Chemiluminescence: Oxygenation and Dioxetanone Formation

open access: yesJournal of Computational Chemistry, Volume 47, Issue 11, 30 April 2026.
Chemiluminescent ADLumin molecules were studied using DFT to investigate their mechanisms of oxygenation and dioxetanone formation. Different oxygenation sites were explored for initiating competing reaction pathways that converge to the same 1,2‐dioxetanone intermediate.
Carly Wickizer   +5 more
wiley   +1 more source

Argon Cold Plasma Modification of Polyethylene Films to Tailor Surface and Barrier Properties

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 16, April 20, 2026.
Argon cold plasma treatment of low‐density polyethylene (LDPE) and high‐density polyethylene (HDPE) films induces major changes in surface chemistry and morphology. Contact angles decrease significantly while surface energy increases, improving wettability. FTIR confirms the formation of polar functional groups, while pronounced etching, roughness, and
Aikaterini Spanou   +11 more
wiley   +1 more source

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