Results 171 to 180 of about 203,537 (274)

Quantum Chemical Exploration of Fentanyl and Its Analogs: Conformational Landscapes and Energetics in Solution. [PDF]

ACS Omega
McKnight KA, Reed EL, Glick CS, Juechter LA, Guevara CA, Scott CE, Shields GC.   +6 more
europepmc   +1 more source

Adults With Acid Sphingomyelinase Deficiency Have Sustained Improvements in Clinical Outcomes With up to 5 Years of Olipudase Alfa Enzyme Replacement Therapy: ASCEND Trial Final Results

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Acid sphingomyelinase deficiency (ASMD) is a rare debilitating lysosomal storage disease resulting in multisystemic disease manifestations, significant disease burden, and early mortality for some individuals. Enzyme replacement therapy (ERT) with olipudase alfa (Xenpozyme) is the first disease‐specific treatment indicated for noncentral ...
Melissa P. Wasserstein, Carla E. Hollak, Antonio Barbato, Renata C. Gallagher, Roberto Giugliani, Norberto Bernardo Guelbert, Julia B. Hennermann, Takayuki Ikezoe, Robin Lachmann, Olivier Lidove, Paulina Mabe, Eugen Mengel, Maurizio Scarpa, Ebubekir Senates, Michel Tchan, Beth L. Thurberg, Jesus Villarrubia, Nicole M. Armstrong, Shashi Bhushan, Yong Kim, Monica Kumar   +20 more
wiley   +1 more source

L’ostéoradionécrose due à des radiothérapies répétées du sein. [PDF]

CMAJ
Lum N, Kwan JYY.
europepmc   +1 more source

Unifying the Communities of Early‐Onset Glycogen Storage Disease Type IV and Adult Polyglucosan Body Disease Through a Genetic Prevalence Study of GBE1‐Related Disease

JIMD Reports, Volume 67, Issue 3, May 2026.
Genetic prevalence study of glycogen storage disease type IV. In collaboration with the Rare Genomes Project at the Broad Institute of MIT and Harvard and the APBD Research Foundation, this study queried and curated variants in GBE1 from ClinVar, HGMD, and gnomAD to calculate the genetic prevalence of glycogen storage disease type IV (GSD IV).
Rebecca L. Koch, H. Orhan Akman, Erin Chown, Deberah Goldman, Jeff Levenson, Qing Lu, Lindsay T. Michalovicz Gill, Matthew Morgan, Jennifer L. Orthmann‐Murphy, Natacha T. Pires, Rebecca Reef, Harriet Saxe, Moriel Singer‐Berk, Samantha Baxter   +13 more
wiley   +1 more source

Redundant ¹⁵N-Mediated <i>J</i>-Couplings Reveal an Aglycone Conformation in <i>N</i>-Phenyl Glycosylamines. [PDF]

J Org Chem
Habanová N, Kaminský J, Parkan K, Zýka J, Prouza V, Klepetářová B, Pohl R.   +6 more
europepmc   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Triplet 4‐Nitrenemethyl‐Pyridine‐N‐Oxide: A Model Alkyl Nitrene Isolated in Cryogenic Matrices

Journal of Physical Organic Chemistry, Volume 39, Issue 5, May 2026.
The simplest triplet alkyl nitrene bearing a pyridine‐N‐oxide moiety was generated by direct irradiation (λ > 350 nm) of the corresponding azide in an Ar matrix at 15 K. Quantum tunneling 1,2‐H shift to the corresponding imine is thermodynamically favorable but does not occur due to a high‐energy barrier (~36 kcal mol−1).
Cláudio M. Nunes, A. J. Lopes Jesus, Tatiana Caneca, Gemma Aragay, Pablo Ballester, Rui Fausto   +5 more
wiley   +1 more source

Thyroïdite de Riedel évoquant une tumeur maligne localement invasive chez un homme de 55 ans. [PDF]

CMAJ
Salinovic D, Pavlicek V, Fleischmann A, Renzulli P.   +3 more
europepmc   +1 more source

Surgical management of an open humeral fracture in a greater rhea (Rhea americana): Internal placement of a locking compression plate and post‐operative complications

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
SUMMARY A 17‐year‐old, 24‐kg, female greater rhea (Rhea americana) presented with an acute onset of left wing droop. Clinical examination and radiographs revealed an open, simple, displaced, short‐oblique diaphyseal fracture of the distal third of the left humerus.
Pierre Huberdeau, Thomas Coutant, Aram Arslanian, Emeline Maurice, Fouad Stephan, Sylvie Laidebeure, Alexis Lécu   +6 more
wiley   +1 more source

Nest Predation in the Canarian Houbara Bustard (Chlamydotis undulata fuertaventurae): An Experimental Study Using Artificial Nests

Ecological Research, Volume 41, Issue 3, May 2026.
We investigated nest predation in the endangered Canarian houbara bustard using 229 artificial nests and camera traps. Ravens were identified as the main predators, and predation rates were influenced by raven density, vegetation cover, stone cover, and road density.
Alberto Ucero, Juan Carlos Alonso, Inmaculada Abril‐Colón   +2 more
wiley   +1 more source