Results 141 to 150 of about 9,391,147 (295)
Quality Control Gone Wrong: Mitochondria, Lysosomal Storage Disorders and Neurodegeneration. [PDF]
, 2013 The eukaryotic cell possesses specialized pathways to turnover and degrade redundant proteins and organelles. Each pathway is unique and responsible for degradation of distinctive cytosolic material.
Duchen, MR, Osellame, LD
core +1 more source
Veterinary Dermatology, Volume 37, Issue 1, Page 140-147, February 2026.Background: Normal hydration of the canine epidermis is imperative for cutaneous homeostasis. Xerosis may be encountered in canine atopic dermatitis and may be aggravated by topical antiseptics. Hypothesis and Objectives: To evaluate the hydrating properties and the safety of a spray (Sensiderm spray; MP Labo) when applied after shampooing healthy dogs
Adamantia Pseftogka +3 more
wiley +1 more source
Molecular Genetics and Metabolism, 2021 Emily C Daykin, Emory Ryan, E. Sidransky
semanticscholar +1 more source
No evidence for substrate accumulation in Parkinson brains with GBA mutations [PDF]
, 2015 To establish whether Parkinson's disease (PD) brains previously described to have decreased glucocerebrosidase activity exhibit accumulation of the lysosomal enzyme's substrate, glucosylceramide, or other changes in lipid ...
Gegg, ME +5 more
core +1 more source
Chemistry – A European Journal, Volume 32, Issue 2, 9 January 2026.A small set of low‐valency multivalent 3,4,5‐trihydroxypiperidines was prepared through double reductive amination (DRA) of a sugar‐derived dialdehyde. Among them, trivalent derivative 37 emerged as a potent β‐glucocerebrosidase (GCase) inhibitor displaying an unexpected mixed‐type kinetic profile. The integration of kinetic analysis, NMR, docking, and
Maria Giulia Davighi +10 more
wiley +1 more source
Treatment options for patients with Gaucher disease
Egyptian Journal of Medical Human Genetics, 2016 Gaucher disease is the most common lysosomal storage disorder due to deficiency of ß-glucocerebrosidase. Since the introduction of Ceredase in 1991, enzyme replacement therapy has been the mainstay of treatment with its major disadvantage of long life ...
Rabah M. Shawky, Solaf M. Elsayed
doaj +1 more source
Gaucher disease with pathological femoral fracture: A case report with review of literature [PDF]
, 2019 Daniel Stoecklin
openalex +1 more source
Gene expression with corresponding pathways analysis in Gaucher disease
, 2021 Łukasz Pawliński +9 more
openalex +2 more sources
Case report: Multidisciplinary collaboration in diagnosis and treatment of child gaucher disease [PDF]
, 2023 Jianfang Zhu +3 more
openalex +1 more source