Results 141 to 150 of about 6,947,949 (386)
Journal of Physics: Conference Series, 2006 Gauge theories are studied on a space of functions with the Moyal-Weyl product. The development of these ideas follows the differential geometry of the usual gauge theories, but several changes are forced upon us. The Leibniz rule has to be changed such that the theory is now based on a twisted Hopf algebra.
openaire +4 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Minimal gauge invariant and gauge fixed actions for massive higher-spin fields
Journal of High Energy Physics, 2019 Inspired by the rich structure of covariant string field theory, we propose a minimal gauge invariant action for general massive integer spin n field. The action consists of four totally symmetric tensor fields of order respectively n, n − 1, n − 2 and n
Masako Asano
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Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Communications in Mathematical Physics, 1983 The author deals with two things: first he defines a class of graded principal fibre bundles, secondly he introduces there some differential operators and studies a Lagrangian of the supergauge field theory. For the purpose of his graded bundles he presents a realization of a super Lie group in the case when a linear representation of its algebra is ...
openaire +3 more sources
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Chiral gauge theory and gravity from unconventional supersymmetry
Journal of High Energy Physics, 2020 From a gauge SU (2, 2|2) model with broken supersymmetry, we construct an action for SU(2)×U (1) Yang-Mills theory coupled to gravity and matter in four dimensions. The connection components for AdS boosts and special conformal translations are auxiliary
Pedro D. Alvarez +2 more
doaj +1 more source
Mitochondrial fatty acid oxidation is stimulated by red light irradiation
FEBS Letters, EarlyView.Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera +4 more
wiley +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source