Results 41 to 50 of about 1,315,232 (288)

Multiplying a Gaussian Matrix by a Gaussian Vector

, 2017
We provide a new and simple characterization of the multivariate generalized Laplace distribution. In particular, this result implies that the product of a Gaussian matrix with independent and identically distributed columns by an independent isotropic ...
Mattei, Pierre-Alexandre
core   +1 more source

Non-Gaussian Error Contribution to Likelihood Analysis of the Matter Power Spectrum [PDF]

, 2010
We study the sample variance of the matter power spectrum for the standard Lambda Cold Dark Matter universe. We use a total of 5000 cosmological N-body simulations to study in detail the distribution of best-fit cosmological parameters and the baryon ...
Atsushi Taruya, Blake, Cooray, Dore, Eisenstein, Eisenstein, Eisenstein, Gaztanaga, Heitmann, Issha Kayo, Jeong, Jeong, Kazin, Kim, Komatsu, Lee, Lewis, Masahiro Takada, Matarrese, Matsubara, Naoki Yoshida, Naoshi Sugiyama, Neyrinck, Nishimichi, Nishimichi, Nomura, Okumura, Pietroni, Rassat, Ryuichi Takahashi, Sato, Scoccimarro, Seo, Seo, Seo, Seo, Shoji, Shun Saito, Smith, Spergel, Takahashi, Takahashi, Takahiko Matsubara, Takahiro Nishimichi, Taruya, Tegmark   +45 more
core   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Log-normal distribution from a process that is not multiplicative but is additive

, 2013
The central limit theorem ensures that a sum of random variables tends to a Gaussian distribution as their total number tends to infinity. However, for a class of positive random variables, we find that the sum tends faster to a log-normal distribution ...
Mouri, H.
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Tails of probability density for sums of random independent variables

, 2001
The exact expression for the probability density $p_{_N}(x)$ for sums of a finite number $N$ of random independent terms is obtained. It is shown that the very tail of $p_{_N}(x)$ has a Gaussian form if and only if all the random terms are distributed ...
A. R. R. Papa, A. V. Nagaev, B. V. Gnedenko, C. Anteneodo, C. Tsallis, I. M. Lifshits, M. F. Shlesinger, M. I. Tribel’skii, M. I. Tribel’skii, Michael I. Tribelsky, R. S. Ellis, T. D. Frank, V. Vinogradov, W. Feller   +13 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Main Paths of Brain Fibers in Diffusion Images Mixed with a Noise to Improve Performance of Tractography Algorithm-Evaluation in Phantom [PDF]

Journal of Biomedical Physics and Engineering
Background: Some voxels may alter the tractography results due to unintentional alteration of noises and other unwanted factors.Objective: This study aimed to investigate the effect of local phase features on tractography results providing data are mixed
Alireza Shirazinodeh, Hadis Faraji, Sam Sharifzadeh Javidi, Amir Homayoun Jafari, Mohammadreza Nazemzadeh, Hamidreza Saligheh Rad   +5 more
doaj   +1 more source

Geometry of Gaussian quantum states

, 2015
We study the Hilbert-Schmidt measure on the manifold of mixed Gaussian states in multi mode continuous variable quantum systems. An analytical expression for the Hilbert-Schmidt volume element is derived. Its corresponding probability measure can be used
Link, Valentin, Strunz, Walter T.
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source