Results 41 to 50 of about 5,026,748 (292)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

The multilinear compound Gaussian distribution [PDF]

2012 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2012
We introduce a novel generalization of the compound Gaussian (CG) (or Gaussian Scale Mixture [1]) distribution which extends the Gaussian component of the CG model to a multilinear distribution. The resulting model, which we call the Multilinear Compound Gaussian (MCG) distribution, subsumes both GSM [1] and the previously developed MICA [3–4 ...
Raghu G. Raj, Alan C. Bovik
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The Analysis of WJ Distribution as an Extended Gaussian Function: Case Study

Applied Sciences, 2022
The double exponential WJ distribution has been shown to competently describe extreme events and critical phenomena, while the Gaussian function has celebrated rich applications in many other fields.
Shurong Ge, Junhua Wu
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Hospital Services Quality Prediction Using A New Deep Fuzzy Learning Model

Mağallaẗ Al-kūfaẗ Al-handasiyyaẗ
Hospital services play a crucial role in people's lives, and continuous improvement in these services is essential. The prediction is paramount to determine the quality and suitability of the hospital's services.
Mohammed K. Al-Khafaji, Eman S. Al-Shamery   +1 more
doaj   +1 more source

Novel Composite Approximation for the Gaussian Q-Function

Elektronika ir Elektrotechnika, 2020
This paper, by using Borjesson’s and Benitez’s approximation of Q-function, presents a novel and improved composite approximation of Q-function with wide applicability.
Zoran H. Peric, Aleksandar V. Markovic, Natasa Z. Kontrec, Stefan R. Panic, Petar C. Spalević   +4 more
doaj   +1 more source

Power Distribution System Synchrophasor Measurements With Non-Gaussian Noises: Real-World Data Testing and Analysis

IEEE Open Access Journal of Power and Energy, 2021
This short paper investigates distribution-level synchrophasor measurement errors with online and offline tests, and mathematically and systematically identifies the actual distribution of the measurement errors through graphical and numerical analysis ...
Can Huang, Charanraj Thimmisetty, Xiao Chen, Emma Stewart, Philip Top, Mert Korkali, Vaibhav Donde, Charles Tong, Liang Min   +8 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source