Results 31 to 40 of about 69,776 (265)
Mediterranean Journal of Clinical Psychology, 2021 Background: Homophobia or the reaction against homosexuals could be based on the structural ideology of the society, on its institutions or on power relationships, which can incite contempt, sometimes even to deadly violence, regarding those not ...
Enrico Perilli +7 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Luang Prabang, sanctuaire Unesco et paradis gay
Genre, Sexualité et Société, 2011 Luang Prabang is a town in Northern Laos that has been on the World Heritage List since 1995. Famous for its Buddhist monasteries and orange-robed monks, as well as for its colonial architecture, its international reputation has grown quickly. It has now
David Berliner
doaj +1 more source
F&S Reports, 2022 Objective: To assess the priorities and decisions of gay and bisexual men pursuing fatherhood. Design: Cross-sectional study. Setting: Internet-based survey.
Brent M. Hanson, M.D. +5 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Les « faux » mariages homosexuels de Sidi Ali au Maroc : enjeux d’un scandale médiatique
Revue des Mondes Musulmans et de la Méditerranée, 2011 The cases of "gay marriages" in Ksar el Kebir and then in Sidi Ali have caused an uproar in the Moroccan press. Beyond the emotions raised by the 'outrageous' mix between the respected institution of marriage and an illegal form of sexuality, this affair
Florence Bergeaud-Blackler, Victor Eck
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Mental Health Professionals and Lesbian, Gay, Bisexual, Transgender, and Queer: Current Scenario
Journal of Psychiatry Spectrum, 2022 Nearly 5% of population identify themselves as lesbian, gay, bisexual, transgender, and queer (LGBTQ). It is important to know what constitutes this subset of the population and also know what constitutes human sexuality.
Chidatma Narayana Arampady +4 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source