Results 51 to 60 of about 1,011,463 (357)

Luang Prabang, sanctuaire Unesco et paradis gay

open access: yesGenre, Sexualité et Société, 2011
Luang Prabang is a town in Northern Laos that has been on the World Heritage List since 1995. Famous for its Buddhist monasteries and orange-robed monks, as well as for its colonial architecture, its international reputation has grown quickly. It has now
David Berliner
doaj   +1 more source

Pathways to fatherhood: evaluating the priorities of self-identified gay and bisexual men pursuing family building options

open access: yesF&S Reports, 2022
Objective: To assess the priorities and decisions of gay and bisexual men pursuing fatherhood. Design: Cross-sectional study. Setting: Internet-based survey.
Brent M. Hanson, M.D.   +5 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Les « faux » mariages homosexuels de Sidi Ali au Maroc : enjeux d’un scandale médiatique

open access: yesRevue des Mondes Musulmans et de la Méditerranée, 2011
The cases of "gay marriages" in Ksar el Kebir and then in Sidi Ali have caused an uproar in the Moroccan press. Beyond the emotions raised by the 'outrageous' mix between the respected institution of marriage and an illegal form of sexuality, this affair
Florence Bergeaud-Blackler, Victor Eck
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Identity, Speech, and Equality [PDF]

open access: yes, 1993
My experience as a litigator tells me that the First Amendment as provided the most reliable path to success of any of the doctrinal claims utilized by lesbian and gay rights lawyers.
Hunter, Nan D.
core   +2 more sources

Mental Health Professionals and Lesbian, Gay, Bisexual, Transgender, and Queer: Current Scenario

open access: yesJournal of Psychiatry Spectrum, 2022
Nearly 5% of population identify themselves as lesbian, gay, bisexual, transgender, and queer (LGBTQ). It is important to know what constitutes this subset of the population and also know what constitutes human sexuality.
Chidatma Narayana Arampady   +4 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Perspectives in laser-driven inertial fusion reactor system

open access: yesAIP Advances
For the first time in any fusion approach, a target gain greater than one was achieved on 5 December 2022 at the National Ignition Facility using lasers in an indirect drive configuration.
X. Ribeyre   +4 more
doaj   +1 more source

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