Results 71 to 80 of about 1,125,334 (390)

Gay men, Gaydar and the commodification of difference [PDF]

open access: yes, 2008
Purpose To investigate ICT mediated inclusion and exclusion in terms of sexuality through a study of a commercial social networking website for gay men Design/methodology/approach The paper uses an approach based on technological inscription and the ...
Alison Adam   +3 more
core   +3 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Mentoring Sexual Minority Youth [PDF]

open access: yes, 2000
It is estimated that up to 10 percent of the U.S. population is lesbian or gay. Thus, one can assume that some of the teenagers being served by mentoring programs are members of this sizeable minority group.
Linda Jucovy
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Gay and bisexual men’s perceptions of the donation and use of human biological samples for research: a qualitative study [PDF]

open access: yes, 2015
Human biological samples (biosamples) are increasingly important in diagnosing, treating and measuring the prevalence of illnesses. For the gay and bisexual population, biosample research is particularly important for measuring the prevalence of human ...
Hilton, Shona   +2 more
core   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Effects of Gay-Themed Advertising among Young Heterosexual Adults from U.S. and South Korea

open access: yesSocial Sciences, 2019
Little research has been conducted to explain the effects of gay-themed advertising in a cross-cultural context. Such research has been particularly scarce in South Korea. This study is designed to investigate the effects of cultural orientation, gender,
Namhyun Um, Dong Hoo Kim
doaj   +1 more source

Longitudinal Event-Level Sexual Risk and Substance Use among Gay, Bisexual, and Other Men Who Have Sex with Men [PDF]

open access: gold, 2021
Jordan M. Sang   +10 more
openalex   +1 more source

When Do Opponents of Gay Rights Mobilize? Explaining Political Participation in Times of Backlash against Liberalism

open access: yes, 2019
Existing research suggests that supporters of gay rights have outmobilized their opponents, leading to policy changes in advanced industrialized democracies.
Ayoub, Phillip M., Page, Douglas D.
core   +2 more sources

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