Results 61 to 70 of about 494,390 (288)
Differentiating the Self: the Kinship Practices of Middle-Aged Gay Men in Manchester [PDF]
, 2013 Middle-aged gay men in Manchester differentiate themselves through accounts of ‘friendship family’ from relating/kinship associated with heterosexuals and younger gay men.
Simpson, Paul
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
European Journal of Investigation in Health, Psychology and Education, 2023 There is currently a lack of measures testing intraminority stress within gay men. Therefore, the current study sought to develop and psychometrically test the Gay-Specific Intraminority Stigma Inventory (G-SISI).
Benjamin F. Shepherd +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Morality, responsibility and risk: Gay men and proximity to HIV. London [PDF]
, 2006 Network analysis and network theory have emerged in various strands of research on HIV. Epidemiological research has used network analysis to map and predict the course of the HIV and STI epidemics among Gay men (Doherty et al. 2005; Piqueira et al. 2004)
Dodds, Catherine +3 more
core
"We Were in a Partnership That Wasn't Recognized by Anyone Else'': Examining the Effects of Male Gay Partner Bereavement, Masculinity, and Identity [PDF]
, 2015 Research with older gay “widowers”1 is relatively rare and the majority focuses on the AIDS/HIV context, rather than on broader causes of death. However, drawing on studies of heterosexual spousal bereavement, we suggest that older widowers are faced ...
Bennett, Kate M +2 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Male homosexuality and borderline personality disorder: a review [PDF]
Journal of Men's HealthGay and bisexual men are more likely than heterosexual men to be diagnosed with borderline personality disorder (BPD). Evidence also suggests an elevated presence of mental health issues and psychological difficulties among gay and bisexual men.
Jaiyant Cavale +2 more
doaj +1 more source
'Tory-normativity' and gay rights advocacy in the British Conservative Party since the 1950s [PDF]
, 2019 Gay rights advocacy in the Conservative party since the 1950s played-down its difference from Conservative beliefs by emphasising pragmatism over emancipation; discretion over celebration; and responsibility over rights.
Monahan, M
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source