Results 41 to 50 of about 18,264 (257)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Héroes, científicos, heterosexuales y gays. [PDF]

open access: yes, 2010
 Óscar Guasch (2006),Héroes, científicos, heterosexuales y gays. Los varones en perspectiva de género, Barcelona, Bellaterra.Óscar Guasch (2006),Héroes, científicos, heterosexuales y gays.
Vendrell Ferré, Joan
core  

Kecemasan sosial kaum Homoseksual Gay dan Lesbian

open access: yesJurnal Ilmiah Psikologi Terapan, 2014
Homosexuality in Indonesia was still considered taboo and socially unaccepted. The common sexual orientation in the society was heterosexual, while homosexual was considered a form of sexual disorientation.
Yogestri Rakhmahappin, Adhyatman Prabowo
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

De Sur a Norte: Chilangos gays en Toronto [PDF]

open access: yes, 2017
"De Sur a Norte. Chilangos gays en Toronto es el tercer libro de Rodrigo Laguarda, y cuyo eje temático –al igual que los dos anteriores- giran en torno a lo que él denomina “homosexualidades masculinas”.
JUAN MIGUEL SARRICOLEA TORRES
core   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

VIOLÊNCIA NA INTIMIDADE NOS RELACIONAMENTOS HOMOSSEXUAIS GAYS E LÉSBICOS

open access: yesPsicologia & Sociedade
Resumo O presente estudo teve como objetivo estudar a prevalência da violência na intimidade nos relacionamentos homossexuais, gays e lésbicos. A amostra foi constituída por 48 participantes de nacionalidade portuguesa, com idades compreendidas entre os ...
Lúcia Osório   +2 more
doaj   +1 more source

The Role Of Doctors And Nurses In Hiv/Aids Handling Efforts Of The Gays

open access: yesSoepra: Jurnal Hukum Kesehatan, 2018
Health was one of the important and main elements in improving community’s welfare. Doctors and nurses were part of health workers providing health services to the community to improve their health status, including in HIV/AIDS handling efforts.
Ludgardis Ramni   +2 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

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