Results 191 to 200 of about 25,057 (208)
Genes, 2021 Mutations of the GBA gene, encoding for lysosomal enzyme glucocerebrosidase (GCase), are the greatest genetic risk factor for Parkinson’s disease (PD) with frequency between 5% and 20% across the world.
Mikhail Nikolaev +2 more
exaly +2 more sources
GBA Variants and Parkinson Disease: Mechanisms and Treatments [PDF]
Cells, 2022 The GBA gene encodes for the lysosomal enzyme glucocerebrosidase (GCase), which maintains glycosphingolipid homeostasis. Approximately 5–15% of PD patients have mutations in the GBA gene, making it numerically the most important genetic risk factor for ...
Laura Smith
exaly +2 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Sphingolipid changes in Parkinson L444P GBA mutation fibroblasts promote α-synuclein aggregation
Brain, 2022Celine Galvagnion, Fabio Blandini
exaly
GBA Variants in Parkinson's Disease: Clinical, Metabolomic, and Multimodal Neuroimaging Phenotypes
Movement Disorders, 2020Marc Tittgemeyer +2 more
exaly
Role of Lysosomal Gene Variants in Modulating GBA-Associated Parkinson's Disease Risk
Movement Disorders, 2022Rosanna Asselta +2 more
exaly
A “dose” effect of mutations in the GBA gene on Parkinson's disease phenotype
Parkinsonism and Related Disorders, 2017Avner Thaler +2 more
exaly
Parkinson's disease phenotype is influenced by the severity of the mutations in the GBA gene
Parkinsonism and Related Disorders, 2018Avner Thaler +2 more
exaly