Results 101 to 110 of about 2,680 (134)

Progression of <i>GBA1</i> severe and risk variants: a longitudinal mixed model analysis. [PDF]

Front Aging Neurosci
Hanff AM, McCrum C, Rauschenberger A, Pachchek S, Aguayo GA, Pauly C, Jónsdóttir SR, Tsurkalenko O, Pauly L, Landoulsi Z, Leist AK, May P, Zeegers MP, Krüger R.   +13 more
europepmc   +1 more source

Editorial: Genetic underpinnings of Alzheimer's and Parkinson's: insights and innovations. [PDF]

Front Genet
Marongiu R, Cordato D, Reiss AB.
europepmc   +1 more source

The genetic architecture of Parkinson's disease on the Island of Crete. [PDF]

NPJ Parkinsons Dis
Boura I, Sait S, Marinakis NM, Arvind K, Chia R, Ray A, Vatsellas G, Loupis T, Pavlaki V, Makrythanasis P, Mitsias P, Xiromerisiou G, Scholz SW, Spanaki C.   +13 more
europepmc   +1 more source

Plasma Glucosylsphingosine in GBA1 E365K, N409S, and L483P Heterozygous Mutation Carriers. [PDF]

Mov Disord
Agin-Liebes J, Haimovich A, Griep R, Hatcher NG, Yao L, Waters C, Padmanabhan S, Alcalay RN.   +7 more
europepmc   +1 more source

Genetic landscape of Parkinson’s disease in the Personalized Parkinson Project cohort

Lüth T, Klein C, Helmich RC, Brüggemann N, Hrir S, Kuiperij HB, Gorgogietas V, Gomes Fernandes SB, Prasuhn J, May P, Outeiro TF, Steidel K, Landoulsi Z, Kleinz T, Schaake S, Much C, Krüger R, Verbeek MM, Bloem BR, van de Warrenburg BP, Trinh J.   +20 more
europepmc   +1 more source

Genetic Testing by Age at Onset in Parkinson Disease.

JAMA Neurol
Balck A, Vollstedt EJ, Westenberger A, Lange LM, Trinh J, Kasten M, Lohmann K, Brüggemann N, Trenkwalder C, Mollenhauer B, Alcalay R, Galvelis KG, Beck JC, Bauer P, Klein C, König IR, Global Parkinson’s Genetics Program (GP2), the ROPAD Study Group, and the PDGENEration Study.   +18 more
europepmc   +1 more source

A Randomized, Double-Blinded, Placebo-Controlled QTc Study to Evaluate BIA 28-6156 Effect on Cardiac Repolarization in Healthy Volunteers. [PDF]

Clin Pharmacol Drug Dev
Peixoto I, Hilt D, Carvalho T, Reis J, Gama H, Holenz J.   +5 more
europepmc   +1 more source

The Race to Salvage Glucocerebrosidase: Understanding Small-Molecule Therapies for GBA1-Associated Parkinsonism. [PDF]

Mov Disord
Henderson MJ, Chen TC, Glasstetter LM, Chen Y, Marugan JJ, Sidransky E.   +5 more
europepmc   +1 more source

Nrf2/NOX2 Pathway Dysregulation and Oxidative Stress Biomarkers in Gaucher Disease-Associated Parkinsonism: Insights Into a Potential Therapeutic Target. [PDF]

J Cell Mol Med
Ardizzone A, Lanza M, Capra AP, Casili G, Bulzomì M, Luca F, Paterniti I, Campolo M, Esposito E.   +8 more
europepmc   +1 more source

Transcriptional changes in the peripheral blood of at-risk individuals without clinical manifestation of Parkinson’s Disease

Whittle B, Chen C, Izuogu O, Jackson M, Santibanez-Koref M, Hudson G.   +5 more
europepmc   +1 more source