Results 71 to 80 of about 15,101 (190)
The protein quality control system in motoneuron diseases [PDF]
, 2015 Spinal and bulbar muscular atrophy (SBMA) is a motoneuronal diseases caused by an elogated polyglutamine (polyQ) tract in the androgen receptor (AR).
Angelo Poletti +8 more
core +1 more source
Journal of Lipid Research, 2016 To date, sterylglucosides have been reported to be present in various fungi, plants, and animals. In bacteria, such as Helicobacter pylori, proton NMR spectral analysis of isolated 1-O-cholesteryl-β-d-glucopyranoside (GlcChol) demonstrated the presence ...
Hisako Akiyama +7 more
doaj +1 more source
Cognition and Synaptic-Plasticity Related Changes in Aged Rats Supplemented with 8- and 10-Carbon Medium Chain Triglycerides. [PDF]
PLoS ONE, 2016 Brain glucose hypometabolism is a common feature of Alzheimer's disease (AD). Previous studies have shown that cognition is improved by providing AD patients with an alternate energy source: ketones derived from either ketogenic diet or supplementation ...
Dongmei Wang, Ellen S Mitchell
doaj +1 more source
P4‐ATPases as Phospholipid Flippases: From Membrane Dynamics to Human Disorders
Medicine Bulletin, Volume 1, Issue 2, Page 121-135, December 2025.ABSTRACT P4‐ATPases (P4 subfamily of P‐type ATPases) flippase complex includes an α‐subunit responsible for catalysis and a supporting β‐subunit, which consumes energy by catalyzing the hydrolysis of ATP, thereby facilitating the translocation of aminophospholipids from the outer to the inner leaflet of cellular membranes to maintain the asymmetric ...
Guangyi Chen, Yeming Yang, Xianjun Zhu
wiley +1 more source
BMC Bioinformatics, 2022 Background We used a hybrid machine learning systems (HMLS) strategy that includes the extensive search for the discovery of the most optimal HMLSs, including feature selection algorithms, a feature extraction algorithm, and classifiers for diagnosing ...
Eskandar Taghizadeh +4 more
doaj +1 more source
Advanced Science, Volume 12, Issue 44, November 27, 2025.The quantitative proteomic and phosphoproteomic profiling reveals dynamic phosphorylation regulation of sperm morphogenesis. Kinase‐substrate phosphorylation network and phosphorylation module analysis, followed by in vivo knockdown and knockout analysis, identify TTBK2 and CSNK1G1 as key regulators of morphogenesis, including head, flagellar, and ...
Tianyu Zhu +25 more
wiley +1 more source
Mediators of Inflammation, 2017 Cystic fibrosis (CF) is the most common autosomal genetic recessive disease caused by mutations of gene encoding for the cystic fibrosis transmembrane conductance regulator.
Domitilla Schiumarini +13 more
doaj +1 more source
Signatures of positive selection underlying beef production traits in Korean cattle breeds
Journal of Animal Science and Technology, 2020 The difference in the breeding programs and population history may have diversely shaped the genomes of Korean native cattle breeds. In the absence of phenotypic data, comparisons of breeds that have been subjected
Zewdu Edea +5 more
doaj +1 more source
Tiling Problems on Baumslag-Solitar groups
, 2013 We exhibit a weakly aperiodic tile set for Baumslag-Solitar groups, and prove that the domino problem is undecidable on these groups. A consequence of our construction is the existence of an arecursive tile set on Baumslag-Solitar groups.Comment: In ...
Aubrun, Nathalie, Kari, Jarkko
core +2 more sources
Molecular Neurodegeneration, 2019 Background Haploinsufficiency in the Gaucher disease GBA gene, which encodes the lysosomal glucocerebrosidase GBA, and ageing represent major risk factors for developing Parkinson’s disease (PD). Recently, more than fifty other lysosomal storage disorder
Mylene Huebecker +6 more
doaj +1 more source