Results 41 to 50 of about 384,770 (213)

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Quantification of PCBs in environmental samples. Comparison of results obtained with different analytical instruments (GC-ECD, GC-MS) and standards

, 1991
Polychlorinated biphenyls have been determined in sediments, macroalgae, mussels and worms sampled in the lagoon of Venice, Italy. Sample preparation included hexane extraction, clean-up with sulphuric acid, Florisil and copper and separation from ...
PAVONI B, RACCANELLI S, SFRISO A.
core   +2 more sources

Box Behnken design-based optimized extraction of non-dioxin-like PCBs for GC-ECD and GC-MS analyses in milk samples

Emerging Contaminants, 2020
A multivariate optimization process of the sample extraction procedure by Box-Behnken design through a global desirability function is described for the determination of six non-dioxin-like polychlorinated biphenyls (NDL-PCBs # 28, 52, 101, 153, 138 and ...
Valeria Nardelli, Valeria D’Amico, Ines Della Rovere, Francesco Casamassima, Wadir Mario Valentino Marchesiello, Donatella Nardiello, Maurizio Quinto   +6 more
doaj   +1 more source

ORGANOCHLORINE INSECTICIDES RESIDUES IN RAW COW’S MILK, CREAM AND BUTTER FROM BENI-SUEF GOVERNORATE [PDF]

Assiut Veterinary Medical Journal, 2016
Organochlorine insecticides residues (α–HCH, β-HCH, Lindane, HCB, Aldrin, Heptachlor, Chlordane, total DDT, Endrin and Methoxychlor) were analyzed in 75 samples of raw milk, sour cream and cooking butter-collected from Beni-Suef Governorate- using gas ...
G.M. HASSAN, SAADIA H.E., A. REFAEE, M. RABEE   +3 more
doaj   +1 more source

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

Advanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong, Wenjun Zhou, Yuxiang Sun, Zihan Huang, Zhiyue Liu, Udhaya Kumar. S, Chenyan Li, Yi Lu, Chengchuang Song, Veronica C. Ciliberto, Makenna Mack, Lana E. Kim, Zhaoyong Hu, Fang Luo, Aihua Cao, Zheng Sun   +15 more
wiley   +1 more source

Optimization of an Analytical Method for Indoxacarb Residues in Fourteen Medicinal Herbs Using GC–μECD, GC–MS/MS and LC–MS/MS

, 2022
Pesticide residue analysis in medicinal herbs is a challenging task because of the matrix effect and its influence on quantitative analysis despite the continuous development of several new analytical methods and instrumentations.
Hun-Ju Ham, Abd Elaziz Sulieman Ahmed Ishag, Syed Wasim Sardar, Jeong-Yoon Choi, Jang-Hyun Hur   +4 more
core   +1 more source

PASSIVE-SAMPLER EMPLOYED FOR ANTIFOULING BOOSTER BIOCIDES ANALYSES IN SEAWATER [PDF]

Química Nova
The antifouling booster biocides are frequently studied for toxic effects on the aquatic ecosystems. The present investigation proposes passive silicone rubber samplers as a collection method for biocides, once these methods can concentrate substances in
Marta S. D. Freitas, Rodrigo M. Batista, Andressa R. C. Costa, Ozelito P. de Amarante Junior, Teresa C. R. S. Franco, Gilberto Fillmann, Natilene M. Brito   +6 more
doaj   +1 more source

Probe‐Free, Primer‐Programmed Amplicon Encoding Enables Nanopore‐Based Multiplex Detection With Deep Learning Decoding

Advanced Science, EarlyView.
Primer‐programmed amplicon encoding enables reporter‐probe‐free multiplex nucleic acid identification using glass nanopore sensing and deep neural network decoding. ABSTRACT Single‐reaction multiplex nucleic acid testing (NATs) must both co‐amplify multiple targets and distinguish the resulting amplicons within the product mixture.
Md. Ahasan Ahamed, Muhammad Asad Ullah Khalid, Wahid Uz Zaman, Anthony J. Politza, Weihua Guan   +4 more
wiley   +1 more source

Evaluation of Uncertainty in the Determination of Pesticide Residues in Tea using GC-ECD

Jurnal Kimia Terapan Indonesia, 2017
Key indicator of quality in test results is the uncertainty value, which could be evaluated using several common approach. Uncertainty evaluation in a-endosulfan and bifenthrin in Oolong tea, and cypermethrin in green tea using bottom-up approach showed that uncertainty component arising from GC-ECD instrument calibration, method performance i.e ...
Ridwan, Yohanes Susanto, Andreas, Andreas, Styarini, Dyah, Yusiasih, Retno   +3 more
openaire   +2 more sources

Dual‐Function Electrocatalysis: Simultaneous Wastewater Remediation and Hydrogen Evolution—A Comprehensive Review

Carbon Energy, EarlyView.
Replacing the oxygen evolution reaction with the electro‐oxidation of pollutants and waste streams offers an energy‐efficient route for simultaneous hydrogen production and pollutant remediation. This review summarizes the reaction mechanisms, catalyst design principles, and emerging paired‐electrolysis strategies that govern activity, selectivity ...
Safa Al‐Yahyaey, Rashid Al‐Hajri, Ala'a H. Al‐Muhtaseb, Hussein A. Younus, Mohammed Al‐Abri   +4 more
wiley   +1 more source