Results 251 to 260 of about 208,701 (315)

Aging‐Driven Immunosuppression: The Role of Tregs in the Ovarian Tumor Microenvironment

Aging Cell, Volume 25, Issue 5, May 2026.
In the aged ovarian TME, cancer cells exhibit increased succinate production. Elevated extracellular succinate activates the SUCNR1 receptor on Tregs, promoting their recruitment and contributing to an immunosuppressive environment. This leads to diminished anti‐tumor T cell responses and reduced survival.
Mary P. Udumula, Anjaly KM, Faraz Rashid, Mohammad Nematullah, Harshit Singh, Tanya Bhardwaj, Miriana Hijaz, Shailendra Giri, Eduardo N. Chini, Heather M. Gibson, Ramandeep Rattan   +10 more
wiley   +1 more source

Difficulties in Diagnosing Gastric Adenocarcinoma of the Cervix: A Clinical Case and Literature Review. [PDF]

Cureus
Gonzalez-Bosquet E, Gonzalez S, Ortiz Peidro L, Sousa Cacheiro SC, Rojo Muchacho LA.   +4 more
europepmc   +1 more source

14‐3‐3σ up‐regulation in the temporal cortex associates with tau pathology and reactive astroglia in Lewy body disorders

Brain Pathology, Volume 36, Issue 3, May 2026.
14‐3‐3 protein homeostasis is disrupted in Lewy body pathology, showing a diminution of six isotypes and overexpression of stratifin. The latter was associated with stratifin colocalization with tau pathology and reactive astrocytes. Platelets, as a peripheral biomarker source, mirrored inversely cortical 14‐3‐3 gene expression patterns in dementia ...
Laura Marsal‐García, Jorge Mena, Carol‐Ann Lao, David Adamuz, Laura Arnaldo, Cristina Carrato, Alex Menendez, Daniela Samaniego, Dolores Vilas, Lourdes Ispierto, Anna Planas, Ramiro Alvarez, Pau Pastor, Katrin Beyer   +13 more
wiley   +1 more source

The Association of Polymyalgia Rheumatica and Giant Cell Arteritis With COVID-19 Vaccination: A Systematic Review. [PDF]

Clin Med Insights Arthritis Musculoskelet Disord
Shahid F, Farooq H, Abeer H, Mahmood GM, Sheikh H, Ameer MZ, Fatima L, Ameer F, Amjad Z, Ahmad TZ, Rehman G, Rehman AU.   +11 more
europepmc   +1 more source

Functional Role of COP1 Gene in Hepatocellular Carcinoma Lipid Metabolism and Stemness

Genes to Cells, Volume 31, Issue 3, May 2026.
COP1 promotes HCC lipid metabolism and stemness via the functional interaction with AKR1D1 and TMEM65 genes, respectively, indicating its potential as a therapeutic target for treating primary HCC and preventing metastasis and/or recurrence. ABSTRACT We have previously defined the constitutive photomorphogenic protein 1 (COP1) gene as a therapeutic ...
Eun‐Hye Jeon, An‐Na Bae, Hajin Lee, Keon Uk Park, Hyun Mu Shin, Jong Ho Park, Kwang Seok Kim, In‐Chul Park, Yun‐Han Lee   +8 more
wiley   +1 more source

Automated detection of giant cell arteritis from temporal artery biopsy specimens using deep learning approaches. [PDF]

Sci Rep
Desingu K, Thuro B, Dhanasekaran N, Bhattaru A, Muralidhar R, Hinkle DM, Yanamala N.   +6 more
europepmc   +1 more source

Understanding the patient experience of newly diagnosed giant cell arteritis. [PDF]

Rheumatol Adv Pract
Lyne SA, Ruediger CD, Hill CL, Shanahan EM.   +3 more
europepmc   +1 more source

Dynamic vascular changes on long-term ultrasound monitoring predict relapse in large-vessel giant cell arteritis. [PDF]

Arthritis Res Ther
Monjo-Henry I, Fernández-Fernández E, Miranda-Carus ME, Nieto-Carvalhal B, Ortíz GT, Molina-Collada J, De Miguel E.   +6 more
europepmc   +1 more source

Recurrent uncomplicated appendicitis in an adult reveals an underlying goblet cell adenocarcinoma: a case report. [PDF]

J Surg Case Rep
Nordström P, Rinta-Kiikka I.
europepmc   +1 more source

Chromosome-level genome assembly of the Leopard Wrasse Macropharyngodon Meleagris. [PDF]

Sci Data
Yu H, Qu M, Li C, Lin Q, Wang D.
europepmc   +1 more source