Results 71 to 80 of about 80,770 (310)

Chemotherapeutic Potential of Fluorouracil‐Platinum (IV) Prodrugs Against Cisplatin‐Resistant Colorectal Cancer Cells

Chemistry – A European Journal, EarlyView.
ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias, Aleen Khoury, Shadma Fatima, Timothy J. Mann, Shawan Karan, Meena Mikhael, Paul de Souza, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich‐Wright   +9 more
wiley   +1 more source

Thermochromic Radiative Cooling Coatings with Robust Superhydrophobicity for Energy‐Efficient Buildings

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A scalable, color‐adaptive radiative cooling coating is developed to enable dynamic spectral regulation via a reversible thermochromic transition at ~45 °C and a high solar reflectance of 91.7%. The coating achieves 4.44 °C outdoor sub‐ambient cooling while providing robust superhydrophobicity and environmental durability through its micro/nano ...
Ziqi Li, Akbar Bashir, Chak‐Yin Tang, Gary Chi‐Pong Tsui, Yan Chen, Jie Cui, Xing Ouyang, Chen Liu, Dazhu Chen   +8 more
wiley   +1 more source

Exploration of High and Low Frequency Options for Subperception Spinal Cord Stimulation Using Neural Dosing Parameter Relationships: The HALO Study

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Subperception spinal cord stimulation (SCS) is described mostly utilizing waveforms that require high energy. However, the necessity of these waveforms for effective subperception has not been established. We aimed to explore whether effective subperception pain relief can be achieved using frequencies below 1 kHz.
José Paz‐Solís, Simon Thomson, Roshini Jain, Lilly Chen, Ismael Huertas, Que Doan   +5 more
wiley   +1 more source

Strumenti, tecniche e soluzioni Open Source a confronto per l’elaborazione fotogrammetrica delle immagini digitali in ambito archeologico

Archeomatica, 2019
This work wants to be an overview about the various “open source” software that can be used to obtain rendering and photogrammetric data geo-referenced from digital photos. In fact, all the phases of digital photogrammetric processing can be performed by
Roberto Montagnetti, Pier Paolo Chiraz, Andrea Ricci, David Gerald Pickel   +3 more
doaj  

ХМАРНІ ПЛАТФОРМИ ЯК КЛЮЧ ДО ЕФЕКТИВНОГО ЗБЕРІГАННЯ ТА АНАЛІЗУ IOT-ДАНИХ

Кібербезпека: освіта, наука, техніка
Стрімкий розвиток Інтернету речей (IoT) спричинив суттєве зростання обсягів даних, що генеруються пристроями, сенсорами та автоматизованими системами. Це створює потребу у високопродуктивних рішеннях для їх зберігання, обробки та аналітики в реальному ...
Іван Кукулевський, Євгеній Сокирка, Андрій Толбатов   +2 more
doaj   +1 more source

Real world testing and cost‐effectiveness analysis of subcutaneous EEG (REAL‐ASE): Protocol for a prospective multicentre interventional trial

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a common condition associated with significant morbidity, mortality, and costs. Poor documentation of seizures is a major challenge in epilepsy care. Objective seizure counting with mobile devices may mitigate this challenge and improve patient management.
Matthew McWilliam, Pedro F. Viana, Eren Dursun, Joe Davies, Joel S. Winston, Jessica Agren, Harutomo Hasegawa, Jonas Duun‐Henriksen, Mark P. Richardson   +8 more
wiley   +1 more source

More than a box to check: Research sponsor and clinical investigator perspectives on making GCP training relevant

Contemporary Clinical Trials Communications, 2020
Background: Good clinical practice (GCP) training is the industry expectation for ensuring quality conduct of registrational clinical trials. However, concerns exist about whether the current structure and delivery of GCP training sufficiently prepares ...
Teresa Swezey, F. Hunter McGuire, Patricia Hurley, Janette Panhuis, Kathy Goldstein, Tina Chuck, Carrie Dombeck, Brian Perry, Christina Brennan, Natasha Phrsai, Amy Corneli   +10 more
doaj   +1 more source

PelviSound L—Real‐time intraoperative sonographic assessment of pelvic sentinel lymph nodes using a drop‐in probe in endometrial and cervical cancer during minimally invasive surgery: A single‐center pilot feasibility study in 20 patients

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Sentinel lymph node biopsy (SLNB) is considered an essential step in the surgical management of endometrial and cervical cancers as it has led to a reduction in the need for full pelvic lymphadenectomy. This proof‐of‐concept study aimed to evaluate the feasibility and diagnostic performance of intraoperative sonographic assessment of
Sascha Hoffmann, Laura Trif, Bernhard Krämer, Felix Neis, Diethelm Wallwiener, Sara Y. Brucker, Markus Hoopmann, Markus Hahn   +7 more
wiley   +1 more source

Inhibition effect of glycyrrhiza polysaccharide (GCP) on tumor growth through regulation of the gut microbiota composition

Journal of Pharmacological Sciences, 2018
Glycyrrhiza Uralensis Polysaccharide (GCP), as a macromolecular polysaccharide extracted from the Traditional Chinese Medicine (TCM) - Licorice has been proved to inhibit tumor growth in vitro and in vivo; however, the specific anti-tumor mechanism of ...
Xiaoyu Zhang, Shuwu Zhao, Xinbo Song, Jianwei Jia, Zhaiyi Zhang, Huifang Zhou, Hui Fu, Huantian Cui, Shuo Hu, Minjie Fang, Xiaomin Liu, Yuhong Bian   +11 more
doaj   +1 more source

On the Meaning of the Principle of General Covariance

, 2012
We present a definite formulation of the Principle of General Covariance (GCP) as a Principle of General Relativity with physical content and thus susceptible of verification or contradiction.
A. Einstein, A. Einstein, Alberto Chamorro, C. Møller, C. Rovelli, C.W. Misner, E. Cartan, E. Kretschmann, E.A. Desloge, G.F.R. Ellis, J. Stachel, J.D. Norton, J.D. Norton, J.L. Anderson, K. Friedrichs, L. Lusanna, R.M. Wald, V. Fock   +17 more
core   +1 more source