Results 51 to 60 of about 29,893 (266)

Мониторинг клинического исследования

Качественная клиническая практика, 2018
Мониторинг (monitoring) — процесс контроля за ходом клинического исследования, призванный гарантировать, то что оно проводится, документируется и информация о нем передается в соответствующие инстанции согласно Протоколу, правилам GCP, стандартным ...

doaj  

More than a box to check: Research sponsor and clinical investigator perspectives on making GCP training relevant

Contemporary Clinical Trials Communications, 2020
Background: Good clinical practice (GCP) training is the industry expectation for ensuring quality conduct of registrational clinical trials. However, concerns exist about whether the current structure and delivery of GCP training sufficiently prepares ...
Teresa Swezey, F. Hunter McGuire, Patricia Hurley, Janette Panhuis, Kathy Goldstein, Tina Chuck, Carrie Dombeck, Brian Perry, Christina Brennan, Natasha Phrsai, Amy Corneli   +10 more
doaj   +1 more source

Advances in Design Strategy and Mechanism Insights for Alkaline Hydrogen Evolution Reaction: Multilevel Site Engineering and Structure–Activity Relationship

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This review is about material design based on engineering multilevel sites from theoretical calculation and synthetic routes to mechanism, structure–activity relationship, challenges and perspectives for boosting hydrogen production in alkaline electrolyte. Electrolytic water splitting is a clean, carbon‐free method for producing green hydrogen and has
Ke Zhang, Hongying Luo, Yudong Du, Kehao Yu, Huayu Wu, Shimin Chai, Yanyan Liu, Yongfeng Wang, Jianchun Jiang, Baojun Li   +9 more
wiley   +1 more source

Real world testing and cost‐effectiveness analysis of subcutaneous EEG (REAL‐ASE): Protocol for a prospective multicentre interventional trial

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a common condition associated with significant morbidity, mortality, and costs. Poor documentation of seizures is a major challenge in epilepsy care. Objective seizure counting with mobile devices may mitigate this challenge and improve patient management.
Matthew McWilliam, Pedro F. Viana, Eren Dursun, Joe Davies, Joel S. Winston, Jessica Agren, Harutomo Hasegawa, Jonas Duun‐Henriksen, Mark P. Richardson   +8 more
wiley   +1 more source

Strumenti, tecniche e soluzioni Open Source a confronto per l’elaborazione fotogrammetrica delle immagini digitali in ambito archeologico

Archeomatica, 2019
This work wants to be an overview about the various “open source” software that can be used to obtain rendering and photogrammetric data geo-referenced from digital photos. In fact, all the phases of digital photogrammetric processing can be performed by
Roberto Montagnetti, Pier Paolo Chiraz, Andrea Ricci, David Gerald Pickel   +3 more
doaj  

Effectiveness and safety of implantable vagus nerve stimulation in people with primary generalized tonic–clonic seizures

Epilepsia Open, EarlyView.
The impact of prompt diagnosis and treatment, and early predictors of outcome severity in this cohort. Abstract Objective Most therapies for drug‐resistant epilepsy (DRE) focus on focal‐onset seizures, the most common seizure types. Studying primary generalized tonic–clonic seizures (PGTCS) is more challenging due to diagnostic and recruitment ...
Katherine Eggleston, Justine Curley, Ryan Verner, Maxine Dibue, Charles Gordon, Gaia Giannicola, Kathryn Nichol   +6 more
wiley   +1 more source

Chiral perovskites for next‐generation chiral optoelectronics and spintronics

FlexMat, EarlyView.
Benefiting from structural inversion symmetry breaking and strong spin‐orbit coupling, chiral perovskites possess intriguing chiral optical and spin properties. We overview their advances and core applications in perovskite solar cells, circularly polarized light detectors and spin circularly polarized‐light‐emitting diodes, offering great potential ...
Mengyao Zhang, Rui Xu, Xueyan Hou, Sihan Du, Mengting Xu, Jia Wu, Zhichao Lin, Pei Liu, Qiang Zhuang, Xiaoming Zhao, Yang Yang, Wenda Shi, Wanlin Guo, Jie Kong   +13 more
wiley   +1 more source

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

International Journal of Cancer, EarlyView.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg, Cathrine L. Lorentzen, Marie C. W. Westergaard, Trine Z. Iversen, Troels H. Borch, Marco Donia, Sigrid M. Mannering, Stine E. W. Banke, Özcan Met, Inge Marie Svane   +9 more
wiley   +1 more source

Influence of ground control point reliability and distribution on UAV photogrammetric 3D mapping accuracy

Geo-spatial Information Science
This study investigates the impacts of Ground Control Points (GCP) reliability, quantity, and distribution on the accuracy of Unmanned Aerial Vehicle (UAV) photogrammetric 3D mapping.
Haonan Zhong, Yansong Duan, Pengjie Tao, Zuxun Zhang   +3 more
doaj   +1 more source

Adjuvant Chemotherapy Regimens in Resected Biliary Tract Cancers: National, Comparative, Observational Study (TOG/GI‐SAFRADJU‐2501)

International Journal of Cancer, EarlyView.
ABSTRACT The recommended adjuvant chemotherapy (adj‐ChT) regimen for resected biliary tract cancers (BTC) is capecitabine (Cape); yet, the recommendation is based on limited evidence. Although varied adj‐ChTs have been employed in practice, robust real‐world data is scarce. We conducted a national, multicenter, hospital‐based registry study to evaluate
Erman Akkus, Mehmet Kayaalp, Müzeyyen Aslı Ergözoğlu, Ilgın Koç Kuş, Doğan Bayram, Bilgeşah Kılıçtaş, Emel Ayvaz Güneyin, Ali Kalem, Haydar Temizyürek, Mehmet Mutlu Çatlı, Mehmet Sinan Akarca, Maral Martin Mıldanoğlu, Görkem Turhan, Mahmut Kara, Hacı Arak, Feyza Arslan Tan, Burak Paçacı, Berkay Yeşilyurt, Orhun Akdoğan, Emine Bihter Çetin, Selahattin Çelik, Fatma Keskin Uzundere, Elif Şahin, Zehra Sadak Öcal, Lamia Şeker Can, Bahadır Köylü, Mehmet Cem Fidan, Esmanur Kaplan Tüzün, Teoman Şakalar, Elif Sertesen Çamöz, Haydar Çağatay Yüksel, Onur Yazdan Balçık, Pınar Peker, Mehmet Yılmaz, Şeymanur Ala Enli, Erdem Kölemen, Sibel Oyucu Orhan, Yakup Düzköprü, Mustafa Ersoy, Tuğba Akın Telli, Mesut Yılmaz, Yusuf İlhan, Atila Yıldırım, Ramazan Coşar, Müslih Ürün, Arif Hakan Önder, Murat Araz, Ertuğrul Bayram, Havva Yeşil Çınkır, Ali Alkan, Mustafa Gürbüz, Nilüfer Avcı, Fatma Paksoy Türköz, İsmail Oğuz Kara, Fatih Köse, İlkay Tuğba Ünek, Ahmet Bilici, Öznur Bal, Şuayib Yalçın, Lorenza Rimassa, Hatime Arzu Yaşar   +60 more
wiley   +1 more source