Results 71 to 80 of about 29,893 (266)

Characterization and bioactivities of a novel polysaccharide obtained from Gracilariopsis lemaneiformis

Anais da Academia Brasileira de Ciências
Gracilariopsis lemaneiformis is a type of red alga that contains seaweed polysaccharide agar. In this study, a novel non-agar seaweed polysaccharide fraction named GCP (short of crude polysaccharide obtained from Gracilariopsis lemaneiformis) was ...
CHEN-SHAN SHI, YA-XIN SANG, GUI-QING SUN, TIAN-YE LI, ZHENG-SI GONG, XIANG-HONG WANG   +5 more
doaj   +1 more source

Impact of Institutional Protocol on Urinary Catheter Outcome Measures in Orthopedic Children Treated With Epidural Analgesia

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Epidural analgesia is commonly used for pain control after major lower‐limb orthopedic surgery in children, but it is associated with a risk of postoperative urinary retention. Consequently, urinary catheters are often placed and left in situ for the full duration of epidural analgesia, despite the potential risks of prolonged ...
Idan Katz, Tomer Talmy, Dor Barami, Tal S. Beckmann, Barry Danino, Yotam Lior, Margaret Ekstein   +6 more
wiley   +1 more source

Pharmacokinetics of Intravenous Melatonin in Preschool‐Aged Pediatric Surgical Patients

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Melatonin may have several beneficial clinical effects in the perioperative setting. In children, it has been studied for preoperative anxiety, postoperative pain, and emergence delirium. Melatonin's pharmacokinetic profile is well‐known in adults, but data in young children are sparse.
Anne Louise de Barros Garioud, Arash Afshari, Lau Romlund Halgreen, Kristian Østergaard Nielsen, Lars Peter Kloster Andersen   +4 more
wiley   +1 more source

Bioequivalence study of two formulations of lurasidone film coated tablets in healthy subjects under fed conditions

Scientific Reports
To define the bioequivalence (BE) of two orally administered film coated tablets containing 40 mg lurasidone hydrochloride. A single-dose, open-label, randomized two-way crossover trial was conducted under fed conditions, with a washout period of at ...
Gökçe Sözer, Muradiye Nacak, Erol Durucu, Wolfgang Martin, Martin Reinsch, Selma Koru, Aydın Erenmemişoğlu   +6 more
doaj   +1 more source

Capturing the Multi‐Decadal Evolution of Glacier–Permafrost Interactions in a High‐Alpine Environment (Ritord, Western Swiss Alps)

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT This study investigates the multi‐decadal evolution of a glacier forefield under permafrost conditions in the Combins Massif (western Swiss Alps). A multi‐method approach based on historical and recent datasets is used to analyze its landform components.
Julie Wee, Hanne Hendrickx, Sebastián Vivero   +2 more
wiley   +1 more source

Prevalence of bedaquiline resistance in patients with drug-resistant tuberculosis: a systematic review and meta-analysis

BMC Infectious Diseases
Background Drug-resistant tuberculosis (TB) remains a major global public health challenge. While bedaquiline (BDQ) offers improved treatment outcomes for patients with multi-drug resistant TB (MDR-TB), its widespread use has led to the emergence of BDQ ...
Xinyang Hu, Zhiwei Wu, Jing Lei, Yanqin Zhu, Jingtao Gao   +4 more
doaj   +1 more source

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

Generalized Cardinal Polishing Splines Signal Reconstruction

Mathematics
Sampling and reconstruction are indispensable processes in signal processing, and appropriate foundations are crucial for spline reconstruction models.
Fangli Sun, Zhanchuan Cai
doaj   +1 more source

Safety of 8‐Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi‐Center, Double‐Blinded, Placebo‐Controlled Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha (Withania somnifera) has been recognized for enhancing physical strength, mental well‐being, and overall vitality. Despite its long‐standing use across generations, some clinical reports have noted occasional adverse events. This study compared the safety and tolerability of Ashwagandha Root Extract (ARE) in healthy adults.
Ketan Pakhale, Jaising Salve, John Ademola, Jose Parraca, Deepak Langade   +4 more
wiley   +1 more source

GCP inspection by Roszdravnadzor

Качественная клиническая практика, 2018
Государственные органы определяют правила проведения клинических исследований лекарственных средств, поэтому обязаны непосредственно контролировать их проведение. Основная форма контроля за клиническими исследованиями лекарственных препаратов со стороны государства - инспекция.
Belousov D.Yu., Zyryanov S.K., Kolbin A.S., Karpenko L.I., Rogov E.S.   +4 more
openaire   +2 more sources