Qualitative assessment of EOB-GD-DTPA and Gd-BT-DO3A MR contrast studies in HCC patients and colorectal liver metastases [PDF]
Infectious Agents and Cancer, 2019 Aim To compare liver-specific EOB-GD-DTPA and liver-non-specific Gd-BT-DO3A MR, in hepatocellular carcinoma (HCC) and liver colorectal metastases. Material and methods Seventy HCC patients with 158 nodules and 90 colorectal liver metastases (mCRC) with ...
Vincenza Granata +9 more
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A Novel Gd-DTPA-conjugated Poly(L-γ-glutamyl-glutamine)-paclitaxel Polymeric Delivery System for Tumor Theranostics [PDF]
Scientific Reports, 2017 The conventional chemotherapeutics could not be traced in vivo and provide timely feedback on the clinical effectiveness of drugs. In this study, poly(L-γ-glutamyl-glutamine)-paclitaxel (PGG-PTX), as a model polymer, was chemically conjugated with Gd ...
Lipeng Gao +13 more
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Gd-DTPA Adsorption on Chitosan/Magnetite Nanocomposites. [PDF]
Nanoscale Res Lett, 2016 The synthesis of the chitosan/magnetite nanocomposites is presented. Composites were prepared by co-precipitation of iron(II) and iron(III) salts by aqueous ammonia in the 0.1 % chitosan solution.
Pylypchuk IeV +3 more
europepmc +2 more sources
Analysis of pharmacokinetics of Gd-DTPA for dynamic contrast-enhanced magnetic resonance imaging. [PDF]
Magn Reson Imaging, 2016 The pharmacokinetics (PK) of the contrast agent Gd-DTPA administered intravenously (i.v.) for contrast-enhanced MR imaging (DCE-MRI) is an important factor for quantitative data acquisition.
Taheri S, Shah NJ, Rosenberg GA.
europepmc +2 more sources
Effect of Mg and Ca on the Stability of the MRI Contrast Agent Gd–DTPA in Seawater
Frontiers in Marine Science, 2018 Gadolinium diethylenetriaminepentaacetic acid (Gd–DTPA) is widely applied as a contrast enhancer in medical MRI. As Gd–DTPA is only minimally captured in wastewater treatment plants (WTPs) or degraded by UV light and other oxidative processes ...
Johan Schijf, Isabel J. Christy
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BMC Cancer, 2012 Background High interstitial fluid pressure (IFP) in the primary tumor is associated with poor disease-free survival in locally advanced cervical carcinoma. A noninvasive assay is needed to identify cervical cancer patients with highly elevated tumor IFP
Hompland Tord +2 more
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Journal of Cardiovascular Magnetic Resonance, 2012 Purpose Myocardial T1 relaxation time (T1 time) and extracellular volume fraction (ECV) are altered in patients with diffuse myocardial fibrosis. The purpose of this study was to perform an intra-individual assessment of normal T1 time and ECV for two ...
Kawel Nadine +6 more
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[Fe-EOB-tCDTA] generates strong contrast in the blood but not in the liver, despite inhibiting cellular [Gd-EOB-DTPA]2- uptake and partial liver excretion [PDF]
European Radiology ExperimentalObjective Iron-based contrast agents (IBCAs) have potential as alternatives to Gd-based contrast agents (GBCAs), intending to address the long-term safety concerns associated with gadolinium.
Fei Ni +5 more
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Gd-DTPA relaxivity depends on macromolecular content
Magnetic Resonance in Medicine, 2000 Mark Henkelman +2 more
exaly +2 more sources
Liver-targeting MRI contrast agent based on galactose functionalized o-carboxymethyl chitosan
Frontiers in Bioengineering and Biotechnology, 2023 Commercial gadolinium (Gd)-based contrast agents (GBCAs) play important role in clinical diagnostic of hepatocellular carcinoma, but their diagnostic efficacy remained improved.
Li Xu +10 more
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