Results 61 to 70 of about 98,210 (227)

Biocompatible Nanocomplexes for Molecular Targeted MRI Contrast Agent

Nanoscale Research Letters, 2009
Accurate diagnosis in early stage is vital for the treatment of Hepatocellular carcinoma. The aim of this study was to investigate the potential of poly lactic acid–polyethylene glycol/gadolinium–diethylenetriamine-pentaacetic acid (PLA–
Yu Dexin, Ma Chunhong, Wang Shaojie, Lu Zaijun, Chen Zhijin, Zhang Na   +5 more
doaj   +1 more source

Integrin αβ–Targeted Dynamic Contrast–Enhanced Magnetic Resonance Imaging Using a Gadolinium-Loaded Polyethylene Gycol–Dendrimer–Cyclic RGD Conjugate to Evaluate Tumor Angiogenesis and to Assess Early Antiangiogenic Treatment Response in a Mouse Xenograft Tumor Model

Molecular Imaging, 2012
The purpose of this study was to validate an integrin α v β 3 –targeted magnetic resonance contrast agent, PEG-G3-(Gd-DTPA) 6 -(cRGD-DTPA) 2 , for its ability to detect tumor angiogenesis and assess early response to antiangiogenic therapy using dynamic ...
Wei-Tsung Chen, Tiffany Ting Fang Shih, Ran-Chou Chen, Shin-Yang Tu, Hsieh Wen-Yuen, Pang-Chyr Yang   +5 more
doaj   +1 more source

Effects of gadolinium-based contrast agents on thyroid hormone receptor action and thyroid hormone-induced cerebellar Purkinje cell morphogenesis

Frontiers in Endocrinology, 2016
Gadolinium (Gd)-based contrast agents (GBCAs) are used in diagnostic imaging to enhance the quality of magnetic resonance imaging or angiography. After intravenous injection, GBCAs can accumulate in the brain.
Noriyuki Koibuchi, Winda Ariyani, Toshiharu Iwasaki, Toshiharu Iwasaki, Wataru Miyazaki, Erdene Khongorzul, Takahito Nakajima, Satomi Kameo, Hiroshi Koyama, Yoshito Tsushima   +9 more
doaj   +1 more source

Evaluation of Phantom Doping Materials in Quantitative Susceptibility Mapping

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To measure magnetic susceptibility (χ) with Quantitative Susceptibility Mapping (QSM) and evaluate its repeatability using four phantom doping materials relevant to QSM applications. Methods A cylindrical phantom was constructed containing vials of agarose gel doped with two paramagnetic materials (ferritin, USPIO) and two diamagnetic ...
Padriac Hooper, Jin Jin, Kieran O'Brien, Monique Tourell, Simon Daniel Robinson, Markus Barth   +5 more
wiley   +1 more source

Synthesis and Physicochemical Characterization of a New Gadolinium Chelate:  The Liver-Specific Magnetic Resonance Imaging Contrast Agent Gd-EOB-DTPA

, 2016
A convenient synthesis of disodium S-[4-(4-ethoxybenzyl)-3,6,9-tris[(carboxy-κO)methyl]-3,6,9-triazaundecandioato)(5-)-κ3N3,N6,N9,κ2O1,O11]gadolinate(2-) (Gd-EOB-DTPA), 1, is reported. This water-soluble complex is presently undergoing phase III clinical
H. Schmitt-Willich (2978094), J. Platzek (2974509), M. Brehm (2978091), D. Sülzle (2974503), B. Radüchel (2974497), A. Müller-Fahrnow (2974518), G. Michl (2974512), Ch. L. J. Ewers (2978088), O. Petrov (2978097)   +8 more
core   +1 more source

Respiratory motion artefacts in Gd-EOB-DTPA (Primovist/Eovist) and Gd-DOTA (Dotarem)-enhanced dynamic phase liver MRI after intensified and standard pre-scan patient preparation: A bi-institutional analysis.

PLoS ONE, 2020
OBJECTIVE:The objective of this study is to evaluate if intensified pre-scan patient preparation (IPPP) that comprises custom-made educational material on dynamic phase imaging and supervised pre-imaging breath-hold training in addition to standard ...
Christian Wybranski, Florian Siedek, Robert Damm, Angelos Gazis, Ortrud Wenzel, Stefan Haneder, Thorsten Persigehl, Susanne Steinhauser, Maciej Pech, Frank Fischbach, Katharina Fischbach   +10 more
doaj   +1 more source

MR imaging of the gastrointestinal tract: value of Gd-DTPA [PDF]

American Journal of Roentgenology, 1988
To determine the value of gadolinium-DTPA (Gd-DTPA) as an MR contrast material for the gastrointestinal tract, we obtained T1-, T2-, and proton-density-weighted MR scans of the abdomen in 20 volunteers before and after oral administration of the compound (10 ml/kg of a 0.5- or 1.0-mM solution).
M, Laniado, W, Kornmesser, B, Hamm, W, Clauss, H J, Weinmann, R, Felix   +5 more
openaire   +2 more sources

Contrast Agents for Enhanced Bioimaging: A Comprehensive Review

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Contrast agents, especially those that are nanoparticle‐based, are revolutionizing bioimaging by enabling highly sensitive, specific, and early‐stage diagnosis of diseases like cancer, using clinical imaging modalities such as CT, MRI, PET, and SPECT.
Paulo Sérgio Taube, Donald Fernandes, Arthur Abinader Vasconcelos, Hugo de Campos Braga, Alan Kelbis Oliveira Lima, José Arnaldo Santana Costa, Karla Furtado Andriani, Ester da Cunha Meira Santos, Antonio Jorge Silva Araújo Junior, Hauster Maximiler Campos de Paula, Wallace Júnio Reis, Kashif Gul, Nida Wahab, Luis Carlos Resio, Elisa Kawana Leal dos Santos, Márcio Peres de Araujo, Matheus Allen P. da Silva, Juliana Paula da Silva   +17 more
wiley   +1 more source

Impact of Recanalization on Liver Hypertrophy after Portal Vein Embolization and the Role of Re‐Embolization

Annals of Gastroenterological Surgery, Volume 10, Issue 4, Page 1309-1319, July 2026.
This retrospective study of 249 patients undergoing hepatectomy after right portal vein embolization (PVE) demonstrated that major recanalization–defined as recanalization more than one segment within the embolized liver–was associated with impaired regeneration of the future liver remnant (FLR).
Masao Uemura, Shimpei Otsuka, Ryo Ashida, Katsuhisa Ohgi, Mihoko Yamada, Rui Sato, Takeshi Aramaki, Akifumi Notsu, Katsuhiko Uesaka, Teiichi Sugiura   +9 more
wiley   +1 more source

Curcumin Attenuates Aroclor 1254‐Induced Oxidative, Genotoxic, and Apoptotic Alterations in HepG2 Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 7, July 2026.
In HepG2 cells, Aroclor 1254 induced oxidative stress, DNA damage, apoptosis, and mutagenicity; co‐treatment with curcumin restored antioxidant defenses (GSH/thiols; SOD, CAT, GPx, GR, TrxR), reduced ROS and comet/8‐OHdG readouts, and attenuated caspase activation, demonstrating curcumin's hepatoprotective and genoprotective modulation of PCB toxicity.
Pınar Erkekoğlu, Selinay Başak Erdemli Köse, Hülya Tezel Yalçın, Deniz Arca Çakır   +3 more
wiley   +1 more source