Results 51 to 60 of about 286,439 (206)

Clinical feasibility of Gd-EOB-DTPA-enhanced MR imaging for assessing liver function: validation with ICG tests and parenchymal cell volume

open access: yes, 2017
Objective: Using Gd-EOB-DTPA-enhanced MRI to assess liver function and validate with indocyanine green (ICG) tests and parenchymal cell volume (PCV). ;Methods: Nineteen patients scheduled for operation were enrolled.
黃新傑;江淑芬;張晉誠;蘇茂源;劉高郎;吳耀銘   +1 more
core   +1 more source

Comparison of the Ability of Gadobenate Dimeglumine and Gadolinium Ethoxybenzyl Dimeglumine to Display the major Features for Noninvasively Diagnosing Hepatocellular Carcinoma According to the LI-RADS 2018v

open access: yesTechnology in Cancer Research & Treatment
Objective To compare the ability of gadolinium ethoxybenzyl dimeglumine (Gd-EOB-DTPA) and gadobenate dimeglumine (Gd-BOPTA) to display the 3 major features recommended by the Liver Imaging Reporting and Data System (LI-RADS 2018v) for diagnosing ...
Wei-Wei Yao MD   +9 more
doaj   +1 more source

A Ratiometric MRI Probe With a Tuned Crosslinked Network for Quantitative Imaging of Physiological pH

open access: yesSmall, EarlyView.
A ratiometric MRI probe comprising a paramagnetic core and a polymer shell crosslinked with tetraethylene glycol dimethacrylate enables the quantitative imaging of physiological pH. The probe shows pH‐independent r1, while pH‐responsive shell volume changes modulate r2.
Ken Kato   +6 more
wiley   +1 more source

Nivolumab-DTPA-Based PD-1 Imaging Reveals Structural and Pathological Changes in Colorectal Carcinoma

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Programmed cell death protein 1 (PD-1) expression is considered a prognostic marker of tumor response to the immuno-blocking therapy. In this study, nivolumab was conjugated with diethylenetriamine pentaacetate (DTPA) via condensation reaction between ...
Danni Li   +8 more
doaj   +1 more source

Advances in research on layered double hydroxides for biomedical applications

open access: yesSmart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang   +13 more
wiley   +1 more source

Vascular and hepatic enhancements at MR imaging: comparison of Gd-EOB-DTPA and Gd-DTPA in the same subjects

open access: yes, 2017
Objective: The objective was to compare vascular and hepatic enhancement differences at magnetic resonance imaging (MRI) between Gd-EOB-DTPA and Gd-DTPA in the same subjects. ;Methods: Ten healthy subjects received dynamic contrast-enhanced MRI (DCE-MRI)
高嘉宏;施庭芳;許昭禹;陳邦斌;魏淑圓;李宣書;梁博欽;林彥亨;游治維   +1 more
core   +1 more source

A Type I Collagen-Targeted MR Imaging Probe for Staging Fibrosis in Crohn’s Disease

open access: yesFrontiers in Molecular Biosciences, 2021
Fibrostenosis is a serious complication of Crohn’s disease (CD), affecting approximately one-half of all patients. Surgical resection is the typical clinical end due to ineffective antifibrotic therapy mainly through anti-inflammatory treatment and ...
Zhoulei Li   +11 more
doaj   +1 more source

Engineering metal‐organic framework‐based smart porous nanoplatforms for targeted therapy and theranostic applications

open access: yesSmart Molecules, EarlyView.
MOFs offer high porosity and tunability for biomedical applications, especially in cancer therapy via ROS generation and targeted delivery. Though toxicity, stability, and scalability remain key clinical challenges. Drug loading in MOFs exceeds 60%–70% with controlled release behavior.
Jagabandhu Bag   +6 more
wiley   +1 more source

Biocompatible Nanocomplexes for Molecular Targeted MRI Contrast Agent

open access: yesNanoscale Research Letters, 2009
Accurate diagnosis in early stage is vital for the treatment of Hepatocellular carcinoma. The aim of this study was to investigate the potential of poly lactic acid–polyethylene glycol/gadolinium–diethylenetriamine-pentaacetic acid (PLA–
Yu Dexin   +5 more
doaj   +1 more source

Integrin αβ–Targeted Dynamic Contrast–Enhanced Magnetic Resonance Imaging Using a Gadolinium-Loaded Polyethylene Gycol–Dendrimer–Cyclic RGD Conjugate to Evaluate Tumor Angiogenesis and to Assess Early Antiangiogenic Treatment Response in a Mouse Xenograft Tumor Model

open access: yesMolecular Imaging, 2012
The purpose of this study was to validate an integrin α v β 3 –targeted magnetic resonance contrast agent, PEG-G3-(Gd-DTPA) 6 -(cRGD-DTPA) 2 , for its ability to detect tumor angiogenesis and assess early response to antiangiogenic therapy using dynamic ...
Wei-Tsung Chen   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy