Crystal structures reveal nucleotide-induced conformational changes in G motifs and distal regions in human guanylate-binding protein 2. [PDF]
Roy S+6 more
europepmc +1 more source
ABSTRACT Alzheimer's disease (AD) is prevalent in the elderly population and characterized by the intracellular accumulation of neurofibrillary tangles (NFTs), composed of tau proteins, and extracellular deposition of beta‐amyloid protein (Aβ). The present study aimed to investigate the neuroprotective effects of melatonin on Aβ42‐induced AD‐like ...
Jiraporn Panmanee+11 more
wiley +1 more source
Downscaled gridded global dataset for gross domestic product (GDP) per capita PPP over 1990-2022. [PDF]
Kummu M+2 more
europepmc +1 more source
Noninnocence of P‐Mesityl substituent, cleavage of a P═C bond and cyclization are observed in reactions of five phosphaalkenes. The observed activation of the C─H bond of the Mesityl substituent and subsequent addition to nonpolymerizable H2C═CPh2 is examined as a potential clue to the polymerization mechanism for P‐Mesityl phosphaalkenes.
Derek P. Gates+3 more
wiley +1 more source
Spatial and socioeconomic patterns of COVID-19 in transition zones between municipalities in eastern Amazonia. [PDF]
Vasconcelos DD+5 more
europepmc +1 more source
Biomass Sources, synthesis techniques, structures, applications, and contribution toward SDG goals of biomass‐derived carbon nanomaterials. ABSTRACT Plant life has dominated this planet from the beginning of time. With over 82% of biomass (BM) coming from plants, primarily trees, plants are the dominant form of life on Earth.
A. F. M. Fahad Halim+5 more
wiley +1 more source
Structural insight into the catalytic mechanism of the bifunctional enzyme l-fucokinase/GDP-fucose pyrophosphorylase. [PDF]
Lin SW+6 more
europepmc +1 more source
Analysis of Relevant Factors Influencing the Development of Pharmacist Human Resources in China: Based on the Time Series Vector Auto-Regression Model. [PDF]
Guo W+7 more
europepmc +1 more source
Nondegradative Synthetic Molecular Glues Enter the Clinic
Proximity‐inducing drugs are a novel therapeutic modality and currently mainly focused on target degradation. Recently, nondegradative molecular glues, inspired by natural products that reprogram cyclophilin A (Cyp A) to inhibit K‐Ras, have entered the clinic.
Maximilian L. Repity+2 more
wiley +1 more source
EPR Study of Gadolinium(III) Complexes with Heteropolyanions: [Gd(SiW11O39)2]13-and [GdP5W30O110]12-
A. Szyczewski+5 more
openalex +1 more source