Results 281 to 290 of about 861,769 (363)

A Proteomics Profiling Reveals the Neuroprotective Effects of Melatonin on Exogenous β‐amyloid‐42 Induced Mitochondrial Impairment, Intracellular β‐amyloid Accumulation and Tau Hyperphosphorylation in Human SH‐SY5Y Cells

open access: yesCell Biology International, EarlyView.
ABSTRACT Alzheimer's disease (AD) is prevalent in the elderly population and characterized by the intracellular accumulation of neurofibrillary tangles (NFTs), composed of tau proteins, and extracellular deposition of beta‐amyloid protein (Aβ). The present study aimed to investigate the neuroprotective effects of melatonin on Aβ42‐induced AD‐like ...
Jiraporn Panmanee   +11 more
wiley   +1 more source

Models for the Anionic Polymerization of P═C Bonds: Cyclization of n‐BuLi‐Initiated MesP═CPh2 and Related Phosphaalkenes with H2C═CPh2

open access: yesChemistry – A European Journal, EarlyView.
Noninnocence of P‐Mesityl substituent, cleavage of a P═C bond and cyclization are observed in reactions of five phosphaalkenes. The observed activation of the C─H bond of the Mesityl substituent and subsequent addition to nonpolymerizable H2C═CPh2 is examined as a potential clue to the polymerization mechanism for P‐Mesityl phosphaalkenes.
Derek P. Gates   +3 more
wiley   +1 more source

Spatial and socioeconomic patterns of COVID-19 in transition zones between municipalities in eastern Amazonia. [PDF]

open access: yesFront Public Health
Vasconcelos DD   +5 more
europepmc   +1 more source

Biomass‐Derived Carbon Nanomaterials: Synthesis and Applications in Textile Wastewater Treatment, Sensors, Energy Storage, and Conversion Technologies

open access: yesCleanMat, EarlyView.
Biomass Sources, synthesis techniques, structures, applications, and contribution toward SDG goals of biomass‐derived carbon nanomaterials. ABSTRACT Plant life has dominated this planet from the beginning of time. With over 82% of biomass (BM) coming from plants, primarily trees, plants are the dominant form of life on Earth.
A. F. M. Fahad Halim   +5 more
wiley   +1 more source

Nondegradative Synthetic Molecular Glues Enter the Clinic

open access: yesChemMedChem, EarlyView.
Proximity‐inducing drugs are a novel therapeutic modality and currently mainly focused on target degradation. Recently, nondegradative molecular glues, inspired by natural products that reprogram cyclophilin A (Cyp A) to inhibit K‐Ras, have entered the clinic.
Maximilian L. Repity   +2 more
wiley   +1 more source

EPR Study of Gadolinium(III) Complexes with Heteropolyanions: [Gd(SiW11O39)2]13-and [GdP5W30O110]12-

open access: gold, 1996
A. Szyczewski   +5 more
openalex   +1 more source

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