Results 51 to 60 of about 24,307 (264)

A descriptive case series of hepatotoxicity associated with CFTR modulators and possible relevance of pharmacogenetic polymorphisms in cystic fibrosis patients

British Journal of Clinical Pharmacology, EarlyView.
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators are widely used in patients with cystic fibrosis and significantly improve respiratory function and quality of life. However, their effectiveness may be limited by liver damage, which sometimes leads to treatment discontinuation, and the mechanisms underlying this remain poorly ...
Clara Laffitte Redondo, Venceslas Bourdin, Abd El Kader Ait Tayeb, Sihem Benaboud, Inès Martins, Caroline Joyau, Myriam Benhamida, Isabelle Sermet‐Gaudelus, Clémence Martin, Pierre Régis Burgel, Céline Verstuyft, Laurent Chouchana, Estelle Ayme‐Dietrich   +12 more
wiley   +1 more source

General Data Protection Regulation Compliance and Privacy Protection in Wearable Health Devices: Challenges and Solutions

Artuklu Health
Introduction: Wearable health devices have transformed personal health management by providing real-time monitoring and personalized care. However, the vast amounts of sensitive data collected by these devices pose significant privacy risks, particularly
Mazlum Özçağdavul
doaj   +1 more source

Towards a GDPR-compliant cloud architecture with data privacy controlled through sticky policies [PDF]

PeerJ Computer Science
Data privacy is one of the biggest challenges facing system architects at the system design stage. Especially when certain laws, such as the General Data Protection Regulation (GDPR), have to be complied with by cloud environments.
M. Emilia Cambronero, Miguel A. Martínez, Luis Llana, Ricardo J. Rodríguez, Alejandro Russo   +4 more
doaj   +2 more sources

Cardiovascular and neuropsychiatric outcomes with PCSK9 inhibitors in atherosclerotic cardiovascular disease: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Study design and main findings. After 1:1 propensity score matching, 60 885 PCSK9 inhibitor users and 60 885 statin‐only users with ASCVD were compared. Kaplan–Meier curves show 12‐month cumulative event‐free survival for MACE, psychiatric disease, and neurodegenerative disease.
Tianshu Gu, Yang Chen, Nan Zhang, Uazman Alam, Riccardo Proietti, Tong Liu, Kang‐Yin Chen, Gregory Y. H. Lip   +7 more
wiley   +1 more source

Clozapine:norclozapine ratio as a marker of metabolic risk and therapeutic response and effect of valproate on clozapine levels

British Journal of Clinical Pharmacology, EarlyView.
Aims Clozapine is the most effective antipsychotic in treatment‐resistant schizophrenia. Clozapine causes weight gain and increased diabetes risk. The role of its metabolite norclozapine and clozapine:norclozapine ratio (CLZ/NCLZ) in metabolic effects has been debated.
Susanna Maria Rask, Miina Lamminmäki, Olli Kampman, Mari Hämäläinen, Eeva Moilanen, Niko Seppälä, Anssi Solismaa   +6 more
wiley   +1 more source

‘It is not a topic that should be assessed by a test’: Understanding teachers' assessment literacy in the teaching of ‘difficult histories’ such as the Holocaust

British Educational Research Journal, EarlyView.
Abstract This paper explores how history teachers in secondary education in England (a) see their role as assessors and (b) how they make decisions about assessing a difficult history: learning about the Holocaust. Assessment literacy (AL) is recognised as a potentially valuable aspect of good teaching and central to supporting students' learning ...
Mary Richardson, Rebecca Hale, Tom Haward, Kwaku Adjepong   +3 more
wiley   +1 more source

GDPR and Canon Law—The Impact of European Union Law on the Canonical Systems for the Protection of the Right to Good Reputation and Privacy

Religions
The paper examines the impact of GDPR on the canonical regulations established by the National Episcopates of EU Member States in accordance with Article 91, paragraph 1 GDPR.
Fabio Balsamo
doaj   +1 more source

Practical Methods of Implementation for the Indispensable Mechanism of GDPR Compliance

Wroclaw Review of Law, Administration and Economics, 2022
New quality that has been delivered by the provisions of General Data Protection Regulation (GDPR) (EU) 2016/679 is intended to secure a higher level of safety for personal data processing operations.
Bańka Michał, Soczyński Tomasz, Wasiak Dariusz   +2 more
doaj   +1 more source

Measuring what matters: Evaluating the impact of curriculum decolonisation initiatives in UK business schools

British Educational Research Journal, EarlyView.
Abstract Curriculum decolonisation has become a prominent feature of equity agendas in UK higher education, yet there remains limited empirical and theoretical work on how such initiatives are evaluated, particularly within business schools. This paper presents one of the first multi‐institutional empirical studies examining how UK business schools ...
Sally Everett, Rachael Carden, Kenisha Linton   +2 more
wiley   +1 more source

Algorithmic management, managerial prerogatives and burden of proof: the quest for the material truth hidden behind the algorithm

Labour & Law Issues, 2020
Technology is changing the methods used by entrepreneurs to manage their human resources. Many employers have already started to dismiss the completely human exercise of their managerial prerogatives, totally or partially delegating them to more or less ...
Giovanni Gaudio
doaj   +1 more source