Results 161 to 170 of about 52,949 (209)

Gefitinib

Reactions Weekly, 2018
Gefitinib is an orally active selective inhibitor epidermal growth factor receptor (EGFR). The large randomised phase III IPASS study (gefitinib 250 mg, daily vs carboplatin and paclitaxel) showed a beneficial effect on progression-free survival (PFS) and quality of life in selected patient populations under the treatment with gefitinib (HR for TKI 0 ...
Rawluk, Justyna, Waller, Cornelius
  +9 more sources

Gefitinib [PDF]

open access: yesReactions Weekly, 2016
Gefitinib is a small molecule that specifically inhibits the tyrosine kinase (TK) activity of the epidermal growth factor receptor (EGFR) type 1 by interfering with the adenosine triphosphate (ATP) binding site.
Una-Cidon, E   +3 more
core   +5 more sources

Gefitinib

Reactions Weekly, 2014
Gefitinib (Iressa®) is a selective inhibitor of epidermal growth factor, a growth factor that plays a pivotal role in the control of cell growth, apoptosis, and angiogenesis. Gefitinib is clinically used for the treatment of chemoresistant non-small cell lung cancer patients.
A F M Motiur, Rahman   +2 more
  +5 more sources

Gefitinib

Drugs, 2002
Gefitinib (ZD1839) is an orally active selective inhibitor of epidermal growth factor receptor tyrosine kinase, an enzyme that regulates intracellular signalling pathways implicated in the proliferation and survival of cancer cells. In human non-small cell lung cancer (NSCLC) cell lines and xenografts, gefitinib dose-dependently inhibited cellular ...
Christine R, Culy, Diana, Faulds
openaire   +2 more sources

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